Potential differences in psychedelic actions based on biological sex

S Shadani, K Conn, ZB Andrews, CJ Foldi - Endocrinology, 2024 - academic.oup.com
The resurgence of interest in psychedelics as treatments for psychiatric disorders
necessitates a better understanding of potential sex differences in response to these …

Sex differences in glutamate transmission and plasticity in reward related regions

AR Kniffin, LA Briand - Frontiers in Behavioral Neuroscience, 2024 - frontiersin.org
Disruptions in glutamate homeostasis within the mesolimbic reward circuitry may play a role
in the pathophysiology of various reward related disorders such as major depressive …

Dopaminergic and anti-estrogenic responses in juvenile steelhead (Oncorhynchus mykiss) exposed to bifenthrin

JT Magnuson, ND Sy, P Tanabe, C Ji, J Gan… - … and Physiology Part C …, 2024 - Elsevier
The frequency of detection and concentrations of bifenthrin, a pyrethroid insecticide, in the
waterways inhabited by the endangered species, steelhead trout (Oncorhynchus mykiss) …

[HTML][HTML] One path, two solutions: Network-based analysis identifies targetable pathways for the treatment of comorbid type II diabetes and neuropsychiatric disorders

A Onisiforou, P Zanos - Computational and Structural Biotechnology …, 2024 - Elsevier
Comorbid diseases complicate patient outcomes and escalate healthcare costs,
necessitating the need for a deeper mechanistic understanding. Neuropsychiatric disorders …

Analysis of molecular identity and function of putative serotonin receptors in the Giant clam (Tridacna crocea) and the potential role of 5-HT1D-like receptor in …

X Yang, Z Noor, S Guo, Z Zhao, B Cai, G Huang, H Ma… - Aquaculture, 2024 - Elsevier
hydroxytryptamine (5-HT) is a secondary metabolite that interacts with a corresponding
receptor, mediating various processes in organisms. However, the molecular function and …

Endogenous 17β-estradiol regulates sexually dimorphic anxiety responses in zebrafish via the HPI axis and 5-HT/DA pathways

H Tao, YY Zhang, YJ Shen, QL Chen… - Frontiers in Marine …, 2025 - frontiersin.org
Anxiety is a multifaceted emotional response exhibited by animals when confronted with
potential threats. Among most vertebrates, including mammals and fish, there is a …

Sex reversal induced by 17β-estradiol may be achieved by regulating the neuroendocrine system of the Pacific white shrimp Penaeus vannamei

T Wang, S Li, Y Yu, F Li - BMC genomics, 2025 - Springer
Due to sexual dimorphism in growth of penaeid shrimp, all-female cultivation is desirable for
the aquaculture industry. 17β-estradiol (E2) has the potential to induce the male-to-female …

Synaptic plasticity and neuroprotection: The molecular impact of flavonoids on neurodegenerative disease progression

SR Kopalli, T Behl, A Kyada, MM Rekha, M Kundlas… - Neuroscience, 2025 - Elsevier
Flavonoids are a broad family of polyphenolic chemicals that are present in a wide variety of
fruits, vegetables, and medicinal plants. Because of their neuroprotective qualities …

Reduced sensitivity to cocaine effects and changes in mesocorticolimbic dopamine receptors in adolescent sexually active female rats

D Agrati, G Marin, L Rehermann, N Uriarte… - …, 2024 - Springer
Objective To examine the impact of cocaine on sexual motivation and behavior of
adolescent and adult female rats, and to determine the dopamine receptors binding in …

Anxiogenic-like effects of coumarin, possibly through the GABAkine interaction pathway: Animal studies with in silico approaches

AAS Prottay, TR Ripu, MN Sarwar, T Rahman… - Behavioural Brain …, 2025 - Elsevier
Background Anxiety disorder is the most common mental illness and a major contributor to
impairment. Thus, there is an urgent need to find novel lead compounds to mitigate anxiety …