Coumarin–triazole hybrids and their biological activities

YL Fan, X Ke, M Liu - Journal of Heterocyclic Chemistry, 2018 - Wiley Online Library
Hybridization is emerged as a promising strategy in the discovery of new drugs, especially
these with complimentary activities and multiple pharmacological targets that are the …

Coumarin triazoles as potential antimicrobial agents

SA Patil, AR Nesaragi, RR Rodríguez-Berrios… - Antibiotics, 2023 - mdpi.com
Currently, in hospitals and community health centers, microbial infections are highly
common diseases and are a leading cause of death worldwide. Antibiotics are generally …

Synthesis, antifungal, antibacterial activity, and computational evaluations of some novel coumarin-1, 2, 4-triazole hybrid compounds

M Karnaš, V Rastija, K Vrandečić, J Čosić… - Journal of Taibah …, 2024 - Taylor & Francis
Effective plant pathogen control presents an important challenge. Pesticide resistance and
associated health and environmental problems demonstrate the need for novel, safe active …

1, 2, 4-triazole: a privileged scaffold for the development of potent antifungal agents-a brief review

C Tratrat - Current topics in medicinal chemistry, 2020 - ingentaconnect.com
Over the past decades, a tremendous rise in invasive fungal infection diseases attributed to
the yeast Candida albicans in immunocompromised individuals poses a seriously …

Comprehensive review on coumarins: Molecules of potential chemical and pharmacological interest

K Ajay Kumar, N Renuka, G Pavithra… - Journal of Chemical …, 2015 - eprints.uni-mysore.ac.in
Coumarins are one of the most important classes of heterocycles that occupies prime
position in synthetic and pharmaceutical chemistry due to their diverse applications. Broad …

Novel quinoline incorporating 1, 2, 4-triazole/oxime hybrids: synthesis, molecular docking, anti-inflammatory, COX inhibition, ulceroginicity and histopathological …

AM Mohassab, HA Hassan, D Abdelhamid… - Bioorganic …, 2017 - Elsevier
A series of novel quinolines incorporating 1, 2, 4-triazole/oxime hybrids were prepared. They
showed remarkable anti-inflammatory activity and exhibited very low incidence of gastric …

Recent developments of coumarin hybrids as anti-fungal agents

XL Hu, Z Xu, ML Liu, LS Feng… - Current topics in …, 2017 - ingentaconnect.com
Fungi place a huge burden on global healthcare systems attributed to the fact that fungal
infections are responsible for the high morbidity and mortality rates in patients who received …

Recent advancement of triazole derivatives and their biological significance.

NS Neha Singhal, PK Sharma, RD Rupesh Dudhe… - 2011 - cabidigitallibrary.org
Article is based on the different pharmacological activity of the triazole ring, from a last
decade a lot of work is going on, on the triazole ring, scientists develop a lot of new …

[PDF][PDF] Novel chromeneimidazole derivatives as antifungal compounds: synthesis and in vitro evaluation

S Thareja, A Verma, A Kalra, S Gosain, PV Rewatkar… - Acta Pol Pharm, 2010 - ptfarm.pl
424 SURESH THAREJA et al. spectra were recorded on a Varian Mercury YH-300 MHz and
using tetramethylsilane (TMS) as the internal standard. Splitting patterns are designated as …

Synthesis, antimicrobial activity and molecular modeling study of 3-(5-amino-(2H)-1, 2, 4-triazol-3-yl]-naphthyridinones as potential DNA-gyrase inhibitors

NG Mohamed, MM Sheha, HY Hassan… - Bioorganic …, 2018 - Elsevier
Four series of triazolylnaphthyridinone derivatives were synthesized as structural surrogates
of nalidixic acid. The targeted derivatives involve: 3-(5-acylamino-2H-1, 2, 4-triazol-3-yl) …