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StrainXpress: strain aware metagenome assembly from short reads
Next-generation sequencing–based metagenomics has enabled to identify microorganisms
in characteristic habitats without the need for lengthy cultivation. Importantly, clinically …
in characteristic habitats without the need for lengthy cultivation. Importantly, clinically …
Exploring high-quality microbial genomes by assembling short-reads with long-range connectivity
Although long-read sequencing enables the generation of complete genomes for
unculturable microbes, its high cost limits the widespread adoption of long-read sequencing …
unculturable microbes, its high cost limits the widespread adoption of long-read sequencing …
Metagenomics binning of long reads using read-overlap graphs
Metagenomics sequencing enables the direct study of microbial communities revealing
important information such as taxonomy and relative abundance of species. Metagenomics …
important information such as taxonomy and relative abundance of species. Metagenomics …
HiFine: integrating Hi-C-based and shotgun-based methods to refine binning of metagenomic contigs
Y Du, F Sun - Bioinformatics, 2022 - academic.oup.com
Motivation Metagenomic binning aims to retrieve microbial genomes directly from
ecosystems by clustering metagenomic contigs assembled from short reads into draft …
ecosystems by clustering metagenomic contigs assembled from short reads into draft …
Exploring high-quality microbial genomes by assembly of linked-reads with high barcode specificity using deep learning
Z Zhang, H Wang, C Yang, Y Huang, Z Yue, Y Chen… - bioRxiv, 2022 - biorxiv.org
De novo assembly of metagenomic sequencing data plays an essential role in elucidating
the genomes of unculturable microbes. Linked-reads, in which short-reads are linked …
the genomes of unculturable microbes. Linked-reads, in which short-reads are linked …
De Novo Assembly of Genomes in Microbiomes: From Amplicons to Whole-Genome Shotgun Sequencing
X Kang - 2024 - pub.uni-bielefeld.de
In recent decades, the rapid progress of DNA sequencing technologies has greatly
propelled metagenomics research. However, a critical bottleneck in current bioinformatics …
propelled metagenomics research. However, a critical bottleneck in current bioinformatics …
Prokrustean Graph: A substring index for rapid k-mer size analysis
A Park, D Koslicki - bioRxiv, 2024 - pmc.ncbi.nlm.nih.gov
Despite the widespread adoption of k-mer-based methods in bioinformatics, understanding
the influence of k-mer sizes remains a persistent challenge. Selecting an optimal k-mer size …
the influence of k-mer sizes remains a persistent challenge. Selecting an optimal k-mer size …
Improving Metagenomic Binning of Long Reads via Feature Fusion and Graph SAGE
J Nie, H Liu, F Huang, H Chen… - 2024 IEEE International …, 2024 - ieeexplore.ieee.org
The advent of advanced metagenome sequencing techniques has enabled the direct study
of microbial communities in their natural habitats, thereby facilitating the acquisition of …
of microbial communities in their natural habitats, thereby facilitating the acquisition of …
Constructing Metagenome-Assembled Genomes and Mobile Genetic Element Host Interactions Using Metagenomic Hi-C
Y Du - 2024 - search.proquest.com
The advent of metagenomic high-throughput chromosome conformation capture
(metagenomic Hi-C or metaHi-C) enables identifying contig-to-contig relationships with …
(metagenomic Hi-C or metaHi-C) enables identifying contig-to-contig relationships with …
Models and Algorithms for Metagenomics Analysis and Plasmid Classification
A Wickramarachchi - 2022 - search.proquest.com
Metagenomics studies have provided key insights into the composition and structure of
microbial communities found in different environments. Among the techniques used to …
microbial communities found in different environments. Among the techniques used to …