StrainXpress: strain aware metagenome assembly from short reads

X Kang, X Luo, A Schönhuth - Nucleic Acids Research, 2022 - academic.oup.com
Next-generation sequencing–based metagenomics has enabled to identify microorganisms
in characteristic habitats without the need for lengthy cultivation. Importantly, clinically …

Exploring high-quality microbial genomes by assembling short-reads with long-range connectivity

Z Zhang, J **ao, H Wang, C Yang, Y Huang… - Nature …, 2024 - nature.com
Although long-read sequencing enables the generation of complete genomes for
unculturable microbes, its high cost limits the widespread adoption of long-read sequencing …

Metagenomics binning of long reads using read-overlap graphs

A Wickramarachchi, Y Lin - RECOMB International Workshop on …, 2022 - Springer
Metagenomics sequencing enables the direct study of microbial communities revealing
important information such as taxonomy and relative abundance of species. Metagenomics …

HiFine: integrating Hi-C-based and shotgun-based methods to refine binning of metagenomic contigs

Y Du, F Sun - Bioinformatics, 2022 - academic.oup.com
Motivation Metagenomic binning aims to retrieve microbial genomes directly from
ecosystems by clustering metagenomic contigs assembled from short reads into draft …

Exploring high-quality microbial genomes by assembly of linked-reads with high barcode specificity using deep learning

Z Zhang, H Wang, C Yang, Y Huang, Z Yue, Y Chen… - bioRxiv, 2022 - biorxiv.org
De novo assembly of metagenomic sequencing data plays an essential role in elucidating
the genomes of unculturable microbes. Linked-reads, in which short-reads are linked …

De Novo Assembly of Genomes in Microbiomes: From Amplicons to Whole-Genome Shotgun Sequencing

X Kang - 2024 - pub.uni-bielefeld.de
In recent decades, the rapid progress of DNA sequencing technologies has greatly
propelled metagenomics research. However, a critical bottleneck in current bioinformatics …

Prokrustean Graph: A substring index for rapid k-mer size analysis

A Park, D Koslicki - bioRxiv, 2024 - pmc.ncbi.nlm.nih.gov
Despite the widespread adoption of k-mer-based methods in bioinformatics, understanding
the influence of k-mer sizes remains a persistent challenge. Selecting an optimal k-mer size …

Improving Metagenomic Binning of Long Reads via Feature Fusion and Graph SAGE

J Nie, H Liu, F Huang, H Chen… - 2024 IEEE International …, 2024 - ieeexplore.ieee.org
The advent of advanced metagenome sequencing techniques has enabled the direct study
of microbial communities in their natural habitats, thereby facilitating the acquisition of …

Constructing Metagenome-Assembled Genomes and Mobile Genetic Element Host Interactions Using Metagenomic Hi-C

Y Du - 2024 - search.proquest.com
The advent of metagenomic high-throughput chromosome conformation capture
(metagenomic Hi-C or metaHi-C) enables identifying contig-to-contig relationships with …

Models and Algorithms for Metagenomics Analysis and Plasmid Classification

A Wickramarachchi - 2022 - search.proquest.com
Metagenomics studies have provided key insights into the composition and structure of
microbial communities found in different environments. Among the techniques used to …