MicroRNAs in development and disease
D Sayed, M Abdellatif - Physiological reviews, 2011 - journals.physiology.org
MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …
introduced an additional level of intricacy to our understanding of gene regulation. There are …
Viruses, microRNAs, and host interactions
RL Skalsky, BR Cullen - Annual review of microbiology, 2010 - annualreviews.org
One of the most significant recent advances in biomedical research has been the discovery
of the∼ 22-nt-long class of noncoding RNAs designated microRNAs (miRNAs). These …
of the∼ 22-nt-long class of noncoding RNAs designated microRNAs (miRNAs). These …
MicroRNAs in common human diseases
Y Li, KV Kowdley - Genomics, Proteomics and Bioinformatics, 2012 - academic.oup.com
MicroRNAs (miRNAs) are a class of short non-coding RNA molecules that have attracted
tremendous attention from the biological and biomedical research communities over the …
tremendous attention from the biological and biomedical research communities over the …
The interplay between viral-derived miRNAs and host immunity during infection
MicroRNAs are short non-coding RNAs that play a crucial role in the regulation of gene
expression during cellular processes. The host-encoded miRNAs are known to modulate the …
expression during cellular processes. The host-encoded miRNAs are known to modulate the …
Existence of a microRNA pathway in anucleate platelets
P Landry, I Plante, DL Ouellet, MP Perron… - Nature structural & …, 2009 - nature.com
Platelets have a crucial role in the maintenance of hemostasis as well as in thrombosis and
vessel occlusion, which underlie stroke and acute coronary syndromes. Anucleate platelets …
vessel occlusion, which underlie stroke and acute coronary syndromes. Anucleate platelets …
Exosomes derived from HIV-1-infected cells contain trans-activation response element RNA
A Narayanan, S Iordanskiy, R Das, R Van Duyne… - Journal of Biological …, 2013 - ASBMB
Exosomes are nano-sized vesicles produced by healthy and virus-infected cells. Exosomes
derived from infected cells have been shown to contain viral microRNAs (miRNAs). HIV-1 …
derived from infected cells have been shown to contain viral microRNAs (miRNAs). HIV-1 …
Viral and cellular microRNAs as determinants of viral pathogenesis and immunity
E Gottwein, BR Cullen - Cell host & microbe, 2008 - cell.com
MicroRNAs (miRNAs) have recently emerged as key posttranscriptional regulators of gene
expression in multicellular eukaryotes. It is increasingly clear that miRNAs of both viral and …
expression in multicellular eukaryotes. It is increasingly clear that miRNAs of both viral and …
HIV-1 transcription and latency: an update
C Van Lint, S Bouchat, A Marcello - Retrovirology, 2013 - Springer
Combination antiretroviral therapy, despite being potent and life-prolonging, is not curative
and does not eradicate HIV-1 infection since interruption of treatment inevitably results in a …
and does not eradicate HIV-1 infection since interruption of treatment inevitably results in a …
Cellular microRNA and P bodies modulate host-HIV-1 interactions
R Nathans, C Chu, AK Serquina, CC Lu, H Cao… - Molecular cell, 2009 - cell.com
Summary MicroRNAs (miRNAs),∼ 22 nt noncoding RNAs, assemble into RNA-induced
silencing complexes (RISCs) and localize to cytoplasmic substructures called P bodies …
silencing complexes (RISCs) and localize to cytoplasmic substructures called P bodies …
The role of RNAi and microRNAs in animal virus replication and antiviral immunity
JL Umbach, BR Cullen - Genes & development, 2009 - genesdev.cshlp.org
The closely related microRNA (miRNA) and RNAi pathways have emerged as important
regulators of virus–host cell interactions. Although both pathways are relatively well …
regulators of virus–host cell interactions. Although both pathways are relatively well …