Responding to the opioid crisis in North America and beyond: recommendations of the Stanford–Lancet Commission
Executive summary The Stanford–Lancet Commission on the North American Opioid Crisis
was formed in response to soaring opioid-related morbidity and mortality in the USA and …
was formed in response to soaring opioid-related morbidity and mortality in the USA and …
Patient outcomes in dose reduction or discontinuation of long-term opioid therapy: a systematic review
JW Frank, TI Lovejoy, WC Becker… - Annals of internal …, 2017 - acpjournals.org
Background: Expert guidelines recommend reducing or discontinuing long-term opioid
therapy (LTOT) when risks outweigh benefits, but evidence on the effect of dose reduction …
therapy (LTOT) when risks outweigh benefits, but evidence on the effect of dose reduction …
Association of dose tapering with overdose or mental health crisis among patients prescribed long-term opioids
Importance Opioid-related mortality and national prescribing guidelines have led to tapering
of doses among patients prescribed long-term opioid therapy for chronic pain. There is …
of doses among patients prescribed long-term opioid therapy for chronic pain. There is …
Opioid withdrawal symptoms, a consequence of chronic opioid use and opioid use disorder: Current understanding and approaches to management
JV Pergolizzi Jr, RB Raffa… - Journal of clinical …, 2020 - Wiley Online Library
What is known and objective Opioid use in the United States has reached unprecedented—
some would even say crisis—levels. Although many individuals use opioid drugs as part of …
some would even say crisis—levels. Although many individuals use opioid drugs as part of …
A review of the opioid epidemic: what do we do about it?
EA Shipton, EE Shipton, AJ Shipton - Pain and therapy, 2018 - Springer
The opioid epidemic, with its noticeable increase in opioid prescriptions and related misuse,
abuse and resultant deaths in the previous 12 years, is a particularly North American …
abuse and resultant deaths in the previous 12 years, is a particularly North American …
[HTML][HTML] Time trends and prescribing patterns of opioid drugs in UK primary care patients with non-cancer pain: a retrospective cohort study
Background The US opioid epidemic has led to similar concerns about prescribed opioids in
the UK. In new users, initiation of or escalation to more potent and high dose opioids may …
the UK. In new users, initiation of or escalation to more potent and high dose opioids may …
[HTML][HTML] Pain during and after COVID-19 in Germany and worldwide: a narrative review of current knowledge
CH Meyer-Frießem, J Gierthmühlen, R Baron… - Pain …, 2021 - journals.lww.com
Pain is a common symptom accompanying the coronavirus disease 2019 (COVID-19)
caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Nonspecific …
caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Nonspecific …
[HTML][HTML] “I'm not gonna pull the rug out from under you”: Patient-provider communication about opioid tapering
In response to increases in harms associated with prescription opioids, opioid prescribing
has come under greater scrutiny, leading many health care organizations and providers to …
has come under greater scrutiny, leading many health care organizations and providers to …
Association between opioid dose variability and opioid overdose among adults prescribed long-term opioid therapy
Importance Attempts to discontinue opioid therapy to reduce the risk of overdose and adhere
to prescribing guidelines may lead patients to be exposed to variability in opioid dosing …
to prescribing guidelines may lead patients to be exposed to variability in opioid dosing …
Opioid withdrawal: role in addiction and neural mechanisms
Withdrawal from opioids involves a negative affective state that promotes maintenance of
drug-seeking behavior and relapse. As such, understanding the neurobiological …
drug-seeking behavior and relapse. As such, understanding the neurobiological …