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Methamphetamine-induced neuronal damage: neurotoxicity and neuroinflammation
B Kim, J Yun, B Park - Biomolecules & therapeutics, 2020 - pmc.ncbi.nlm.nih.gov
Methamphetamine (METH) is a highly addictive psychostimulant and one of the most widely
abused drugs worldwide. The continuous use of METH eventually leads to drug addiction …
abused drugs worldwide. The continuous use of METH eventually leads to drug addiction …
The transcription factor Zif268/Egr1, brain plasticity, and memory
The capacity to remember our past experiences and organize our future draws on a number
of cognitive processes that allow our brain to form and store neural representations that can …
of cognitive processes that allow our brain to form and store neural representations that can …
Using c-fos to study neuronal ensembles in corticostriatal circuitry of addiction
Learned associations between drugs and environment play an important role in addiction
and are thought to be encoded within specific patterns of sparsely distributed neurons called …
and are thought to be encoded within specific patterns of sparsely distributed neurons called …
Animal models of post-traumatic stress disorder and recent neurobiological insights
Post-traumatic stress disorder (PTSD) is a complex psychiatric disorder characterized by the
intrusive re-experiencing of past trauma, avoidant behavior, enhanced fear, and …
intrusive re-experiencing of past trauma, avoidant behavior, enhanced fear, and …
Cell-type-specific adaptions in striatal medium-sized spiny neurons and their roles in behavioral responses to drugs of abuse
MC Allichon, V Ortiz, P Pousinha… - Frontiers in synaptic …, 2021 - frontiersin.org
Drug addiction is defined as a compulsive pattern of drug-seeking-and taking-behavior, with
recurrent episodes of abstinence and relapse, and a loss of control despite negative …
recurrent episodes of abstinence and relapse, and a loss of control despite negative …
Breast tumor-associated osteoblast-derived CXCL5 increases cancer progression by ERK/MSK1/Elk-1/snail signaling pathway
YL Hsu, MF Hou, PL Kuo, YF Huang, EM Tsai - Oncogene, 2013 - nature.com
The skeleton is the most common metastatic site for breast cancer, with bone metastasis
causing pain as well as risk of pathological fractures. Interaction between tumors and the …
causing pain as well as risk of pathological fractures. Interaction between tumors and the …
Convergence of dopamine and glutamate signaling onto striatal ERK activation in response to drugs of abuse
Despite their distinct targets, all addictive drugs commonly abused by humans evoke
increases in dopamine (DA) concentration within the striatum. The main DA Guanine …
increases in dopamine (DA) concentration within the striatum. The main DA Guanine …
[HTML][HTML] RGS14 regulation of post-synaptic signaling and spine plasticity in brain
NH Harbin, SN Bramlett, C Montanez-Miranda… - International Journal of …, 2021 - mdpi.com
The regulator of G-protein signaling 14 (RGS14) is a multifunctional signaling protein that
regulates post synaptic plasticity in neurons. RGS14 is expressed in the brain regions …
regulates post synaptic plasticity in neurons. RGS14 is expressed in the brain regions …
Molecular mechanism: ERK signaling, drug addiction, and behavioral effects
Addiction to psychostimulants has been considered as a chronic psychiatric disorder
characterized by craving and compulsive drug seeking and use. Over the past two decades …
characterized by craving and compulsive drug seeking and use. Over the past two decades …
The absence of VGLUT3 predisposes to cocaine abuse by increasing dopamine and glutamate signaling in the nucleus accumbens
Tonically active cholinergic interneurons (TANs) from the nucleus accumbens (NAc) are
centrally involved in reward behavior. TANs express a vesicular glutamate transporter …
centrally involved in reward behavior. TANs express a vesicular glutamate transporter …