Norovirus: an overview of virology and preventative measures

N Winder, S Gohar, M Muthana - Viruses, 2022 - mdpi.com
Norovirus (NoV) is an enteric non-enveloped virus which is the leading cause of
gastroenteritis across all age groups. It is responsible for around 200,000 deaths annually …

Genetic susceptibility to human norovirus infection: an update

J Nordgren, L Svensson - Viruses, 2019 - mdpi.com
Noroviruses are the most common etiological agent of acute gastroenteritis worldwide.
Despite their high infectivity, a subpopulation of individuals is resistant to infection and …

Molecular surveillance of norovirus, 2005–16: an epidemiological analysis of data collected from the NoroNet network

J van Beek, M de Graaf, H Al-Hello, DJ Allen… - The Lancet Infectious …, 2018 - thelancet.com
Background The development of a vaccine for norovirus requires a detailed understanding
of global genetic diversity of noroviruses. We analysed their epidemiology and diversity …

Norovirus illness is a global problem: emergence and spread of norovirus GII. 4 variants, 2001–2007

JJ Siebenga, H Vennema, DP Zheng… - The Journal of …, 2009 - academic.oup.com
Abstract Background Noroviruses (NoVs) are the most common cause of viral
gastroenteritis. Their high incidence and importance in health care facilities result in a great …

Mechanisms of GII. 4 norovirus persistence in human populations

LC Lindesmith, EF Donaldson, AD LoBue… - PLoS …, 2008 - journals.plos.org
Background Noroviruses are the leading cause of viral acute gastroenteritis in humans,
noted for causing epidemic outbreaks in communities, the military, cruise ships, hospitals …

Recombination within the pandemic norovirus GII. 4 lineage

JS Eden, MM Tanaka, MF Boni, WD Rawlinson… - Journal of …, 2013 - Am Soc Microbiol
Norovirus (NoV) is the leading cause of viral gastroenteritis globally. Since 1996, NoV
variants of a single genetic lineage, GII. 4, have been associated with at least six pandemics …

Rapid evolution of pandemic noroviruses of the GII. 4 lineage

RA Bull, JS Eden, WD Rawlinson, PA White - PLoS pathogens, 2010 - journals.plos.org
Over the last fifteen years there have been five pandemics of norovirus (NoV) associated
gastroenteritis, and the period of stasis between each pandemic has been progressively …

Epochal evolution of GGII. 4 norovirus capsid proteins from 1995 to 2006

JJ Siebenga, H Vennema, B Renckens… - Journal of …, 2007 - Am Soc Microbiol
Noroviruses are the causative agents of the majority of viral gastroenteritis outbreaks in
humans. During the past 15 years, noroviruses of genotype GGII. 4 have caused four …

Immunogenetic mechanisms driving norovirus GII. 4 antigenic variation

LC Lindesmith, M Beltramello, EF Donaldson… - PLoS …, 2012 - journals.plos.org
Noroviruses are the principal cause of epidemic gastroenteritis worldwide with GII. 4 strains
accounting for 80% of infections. The major capsid protein of GII. 4 strains is evolving …

Norovirus recombination

RA Bull, MM Tanaka, PA White - Journal of General …, 2007 - microbiologyresearch.org
RNA recombination is a significant driving force in viral evolution. Increased awareness of
recombination within the genus Norovirus of the family Calicivirus has led to a rise in the …