Artificial intelligence and machine learning assisted drug delivery for effective treatment of infectious diseases

S He, LG Leanse, Y Feng - Advanced Drug Delivery Reviews, 2021 - Elsevier
In the era of antimicrobial resistance, the prevalence of multidrug-resistant microorganisms
that resist conventional antibiotic treatment has steadily increased. Thus, it is now …

Drug resistance mutations in HIV: new bioinformatics approaches and challenges

L Blassel, A Zhukova, CJ Villabona-Arenas… - Current opinion in …, 2021 - Elsevier
Highlights•Machine learning is increasingly used to predict and understand drug resistance
in HIV.•Phylogenetics helps to track the emergence and spread of HIV drug resistance …

The virtual doctor: an interactive clinical-decision-support system based on deep learning for non-invasive prediction of diabetes

S Spänig, A Emberger-Klein, JP Sowa… - Artificial intelligence in …, 2019 - Elsevier
Artificial intelligence (AI) will pave the way to a new era in medicine. However, currently
available AI systems do not interact with a patient, eg, for anamnesis, and thus are only used …

Ensemble-GNN: federated ensemble learning with graph neural networks for disease module discovery and classification

B Pfeifer, H Chereda, R Martin, A Saranti… - …, 2023 - academic.oup.com
Federated learning enables collaboration in medicine, where data is scattered across
multiple centers without the need to aggregate the data in a central cloud. While, in general …

[HTML][HTML] Drug resistance prediction using deep learning techniques on HIV-1 sequence data

MC Steiner, KM Gibson, KA Crandall - Viruses, 2020 - mdpi.com
The fast replication rate and lack of repair mechanisms of human immunodeficiency virus
(HIV) contribute to its high mutation frequency, with some mutations resulting in the evolution …

Tackling the antimicrobial resistance “pandemic” with machine learning tools: a summary of available evidence

D Rusic, M Kumric, A Seselja Perisin, D Leskur, J Bukic… - Microorganisms, 2024 - mdpi.com
Antimicrobial resistance is recognised as one of the top threats healthcare is bound to face
in the future. There have been various attempts to preserve the efficacy of existing …

Effective prediction of drug–target interaction on HIV using deep graph neural networks

B Das, M Kutsal, R Das - Chemometrics and Intelligent Laboratory Systems, 2022 - Elsevier
Individuals infected with HIV are controlled by drugs known as antiretroviral therapy by
suppressing the amount of HIV in the body. Therefore, studies to predict both HIV-drug …

geno2pheno [ngs-freq]: a genotypic interpretation system for identifying viral drug resistance using next-generation sequencing data

M Döring, J Büch, G Friedrich, A Pironti… - Nucleic acids …, 2018 - academic.oup.com
Identifying resistance to antiretroviral drugs is crucial for ensuring the successful treatment of
patients infected with viruses such as human immunodeficiency virus (HIV) or hepatitis C …

HIV drug resistance prediction with weighted categorical kernel functions

E Ramon, L Belanche-Muñoz, M Pérez-Enciso - BMC bioinformatics, 2019 - Springer
Background Antiretroviral drugs are a very effective therapy against HIV infection. However,
the high mutation rate of HIV permits the emergence of variants that can be resistant to the …

[HTML][HTML] Web service for HIV drug resistance prediction based on analysis of amino acid substitutions in main drug targets

AI Paremskaia, AV Rudik, DA Filimonov, AA Lagunin… - Viruses, 2023 - mdpi.com
Predicting viral drug resistance is a significant medical concern. The importance of this
problem stimulates the continuous development of experimental and new computational …