Rational design of cancer nanomedicine for simultaneous stealth surface and enhanced cellular uptake
Q **, Y Deng, X Chen, J Ji - Acs Nano, 2019 - ACS Publications
Owing to the complex and still not fully understood physiological environment, the
development of traditional nanosized drug delivery systems is very challenging for precision …
development of traditional nanosized drug delivery systems is very challenging for precision …
Poly (β‐Amino Esters): synthesis, formulations, and their biomedical applications
Abstract Poly (β‐amino ester)(abbreviated as PBAE or PAE) refers to a polymer synthesized
from an acrylate and an amine by Michael addition and has properties inherent to tertiary …
from an acrylate and an amine by Michael addition and has properties inherent to tertiary …
Molecular motion in aggregates: manipulating TICT for boosting photothermal theranostics
Planar donor and acceptor (D–A) conjugated structures are generally believed to be the
standard for architecting highly efficient photothermal theranostic agents, in order to restrict …
standard for architecting highly efficient photothermal theranostic agents, in order to restrict …
Dual‐Locking nanoparticles disrupt the PD‐1/PD‐L1 pathway for efficient cancer immunotherapy
The clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR‐associated
(Cas) enzyme, Cas13a, holds great promise in cancer treatment due to its potential for …
(Cas) enzyme, Cas13a, holds great promise in cancer treatment due to its potential for …
Surface-adaptive zwitterionic nanoparticles for prolonged blood circulation time and enhanced cellular uptake in tumor cells
Recently, zwitterionic materials have been developed as alternatives to PEG for prolonging
the circulation time of nanoparticles without triggering immune responses. However …
the circulation time of nanoparticles without triggering immune responses. However …
Nanoprobes with aggregation-induced emission for theranostics
W Wu, Z Li - Materials Chemistry Frontiers, 2021 - pubs.rsc.org
Theranostics is the integration of diagnosis and therapy, which significantly reduces side
effects, and saves time and cost. During the past few years, nanoprobes (NPs) with …
effects, and saves time and cost. During the past few years, nanoprobes (NPs) with …
Co‐delivery of an amyloid‐disassembling polyphenol cross‐linked in a micellar shell with core‐loaded antibiotics for balanced biofilm dispersal and killing
Amyloid‐fibers help to maintain the structure of infectious biofilms. Disassembly of amyloid‐
fibers contributes to biofilm‐dispersal in the blood‐circulation, from which bacteria should be …
fibers contributes to biofilm‐dispersal in the blood‐circulation, from which bacteria should be …
Dual pH-responsive-charge-reversal micelle platform for enhanced anticancer therapy
J Liao, H Peng, C Liu, D Li, Y Yin, B Lu, H Zheng… - Materials Science and …, 2021 - Elsevier
A novel nanodrug delivery system (NDDS) based on block copolymers of Poly (DEA)-block-
Poly (PgMA)(PDPP) was developed to enhance in vitro cellular uptake and anticancer …
Poly (PgMA)(PDPP) was developed to enhance in vitro cellular uptake and anticancer …
[HTML][HTML] Synergy between pH-and hypoxia-responsiveness in antibiotic-loaded micelles for eradicating mature, infectious biofilms
L Su, Y Li, S Tian, F Huang, Y Ren, C Yang… - Acta Biomaterialia, 2022 - Elsevier
Antibiotic-loaded PEG/PAE-based micelles are frequently considered for eradicating
infectious biofilms. At physiological pH, PEG facilitates transport through blood. Near an …
infectious biofilms. At physiological pH, PEG facilitates transport through blood. Near an …
[HTML][HTML] Green tea catechin-based complex micelles combined with doxorubicin to overcome cardiotoxicity and multidrug resistance
Chemotherapy for cancer treatment has been demonstrated to cause some side effects on
healthy tissues and multidrug resistance of the tumor cells, which greatly limits therapeutic …
healthy tissues and multidrug resistance of the tumor cells, which greatly limits therapeutic …