Robust brain development requires the tight coordination between tissue growth, neuronal
differentiation and stem cell maintenance. To achieve this, neural stem cells need to balance …

Adult stem cells depend on their niches for regulatory signaling that controls their
maintenance, division, and their progeny differentiation. While communication between …

Polarized cells rely on a polarized cytoskeleton to function. Yet, how cortical polarity cues
induce cytoskeleton polarization remains elusive. Here, we capitalized on recently …

The phenomenal diversity of neuronal types in the central nervous system is achieved in
part by the asymmetric division of neural precursors. In zebrafish neural precursors …

Asymmetric cell division gives rise to two daughter cells that inherit different determinants,
thereby acquiring different fates. Polarized trafficking of endosomes containing fate …

Melanocytes are neuroectoderm-derived pigment-producing cells with highly polarized
dendritic morphology. They protect the skin against ultraviolet radiation by providing melanin …

Symmetric and asymmetric cell divisions are conserved strategies for stem cell expansion
and the generation of more committed progeny, respectively. Here, we demonstrate that in …

During brain development, progenitor cells need to balanceproliferation and differentiation
in order to generate different neurons in the correct numbers and proportions. Currently, the …

Vertebrate radial glia progenitors (RGPs), the principal neural stem cells, balance self-
renewal and differentiation through asymmetric cell division (ACD), during which unequal …

Asymmetric cell division (ACD) is fundamental for balancing cell proliferation and
differentiation in metazoans. During active neurogenesis in the develo** zebrafish …