Interleukin-17 (IL-17) is an essential proinflammatory cytokine, which is mainly secreted by
the CD4+ helper T cells (Th17 cells) and subsets of innate lymphoid cells. IL-17A is …

Psoriasis has long been known as a disease with many complications, but was attributed to
diet and obesity. However, in recent years, psoriasis itself has been recognized as a series …

Psoriasis is a chronic, inflammatory, multisystem disease that affects up to 3.2% of the US
population. This guideline addresses important clinical questions that arise in psoriasis …

Background Few existing studies on the global incidence, prevalence, and burden of
disease from psoriasis are of high quality, making reliable data and comparisons difficult to …

A convincing deal of evidence supports the fact that severe psoriasis is associated with
cardiovascular diseases. However, the precise underlying mechanisms linking psoriasis …

Psoriasis is a T helper type 17 autoimmune disease associated with an increased risk
cardiovascular events and mortality. Ustekinumab, an antibody to p40, blocks cytokines IL …

Background Patients with psoriasis require long-term management; therefore,
understanding the long-term safety of new treatments, such as bimekizumab (BKZ), is …

Psoriasis, a chronic immune-mediated disease, is associated with an increased risk of
cardiovascular events and mortality. Secukinumab selectively neutralizes IL-17A and has …

Background Coronavirus disease 2019 (COVID-19) is commonly associated with skin
manifestations, and may also exacerbate existing skin diseases, yet the relationship …

Psoriasis is a systemic inflammatory disease significantly associated with comorbidities
including type 2 diabetes mellitus (T2DM). Metformin is utilized as a first-line agent for …