SeGraM: A universal hardware accelerator for genomic sequence-to-graph and sequence-to-sequence map**

DS Cali, K Kanellopoulos, J Lindegger… - Proceedings of the 49th …, 2022 - dl.acm.org
A critical step of genome sequence analysis is the map** of sequenced DNA fragments
(ie, reads) collected from an individual to a known linear reference genome sequence (ie …

Emerging spintronics phenomena and applications

R Mishra, H Yang - IEEE Transactions on Magnetics, 2020 - ieeexplore.ieee.org
Development of future sensor, memory, and computing nanodevices based on novel
physical concepts is one of the significant research endeavors in solid-state research. The …

WFA-FPGA: An efficient accelerator of the wavefront algorithm for short and long read genomics alignment

A Haghi, S Marco-Sola, L Alvarez… - Future Generation …, 2023 - Elsevier
In the last years, advances in genome sequencing technologies have enabled the
proliferation of genomic applications that guide personalized medicine. These applications …

An FPGA accelerator of the wavefront algorithm for genomics pairwise alignment

A Haghi, S Marco-Sola, L Alvarez… - … Conference on Field …, 2021 - ieeexplore.ieee.org
In the last years, advances in next-generation sequencing technologies have enabled the
proliferation of genomic applications that guide personalized medicine. These applications …

Accelerating genome analysis via algorithm-architecture co-design

O Mutlu, C Firtina - 2023 60th ACM/IEEE Design Automation …, 2023 - ieeexplore.ieee.org
High-throughput sequencing (HTS) technologies have revolutionized the field of genomics,
enabling rapid and cost-effective genome analysis for various applications. However, the …

TALCO: tiling genome sequence alignment using convergence of traceback pointers

S Walia, C Ye, A Bera, D Lodhavia… - … Symposium on High …, 2024 - ieeexplore.ieee.org
Pairwise sequence alignment is one of the most fundamental and computationally intensive
steps in genome analysis. With the improving costs and throughput of third-generation …

Genpip: In-memory acceleration of genome analysis via tight integration of basecalling and read map**

H Mao, M Alser, M Sadrosadati, C Firtina… - 2022 55th IEEE/ACM …, 2022 - ieeexplore.ieee.org
Nanopore sequencing is a widely-used high-throughput genome sequencing technology
that can sequence long fragments of a genome into raw electrical signals at low cost …

Aligner-d: Leveraging in-dram computing to accelerate dna short read alignment

F Zhang, S Angizi, J Sun, W Zhang… - IEEE Journal on …, 2023 - ieeexplore.ieee.org
DNA short read alignment task has become a major sequential bottleneck to humongous
amounts of data generated by next-generation sequencing platforms. In this paper, an …

Experimental demonstration of magnetic tunnel junction-based computational random-access memory

Y Lv, BR Zink, RP Bloom, H Cılasun, P Khanal… - npj Unconventional …, 2024 - nature.com
The conventional computing paradigm struggles to fulfill the rapidly growing demands from
emerging applications, especially those for machine intelligence because much of the …

RawHash: enabling fast and accurate real-time analysis of raw nanopore signals for large genomes

C Firtina, N Mansouri Ghiasi, J Lindegger… - …, 2023 - academic.oup.com
Nanopore sequencers generate electrical raw signals in real-time while sequencing long
genomic strands. These raw signals can be analyzed as they are generated, providing an …