In the 1970s, an unknown virus was suspected for documented cases of transfusion-
associated hepatitis, a phenomenon called non-A, non-B hepatitis. In 1989, the infectious …

The discovery of hepatitis C virus (HCV) in 1989 permitted basic research to unravel critical
components of a complex life cycle for this important human pathogen. HCV is a highly …

Hepatocellular carcinoma (HCC) is the primary liver cancer derived from hepatocytes and
accounts for 85–90% of all primary liver cancers. It is the 5th common cancer in men and the …

In the early 1900s, numerous seminal publications reported that high rates of cancer
occurred in certain occupations. During this period, work with infectious agents produced …

Background and Methods To detect potentially curable cases of hepatocellular carcinoma,
outpatients with chronic hepatitis or compensated liver cirrhosis who were seen at the …

Hepatocellular carcinoma (HCC) is the commonest primary malignant cancer of the liver in
the world. Given that the burden of chronic liver disease is expected to rise owing to …

Background: The incidence of hepatocellular carcinoma was reported to be increasing in the
United States. However, alternate explanations were diagnostic or reclassification bias and …

Hepatitis C virus (HCV) accounts for approximately 20% of cases of acute hepatitis, 70% of
chronic hepatitis, and 30% of end-stage liver disease in the United States. The acute …

Hepatitis C has emerged in recent years as the most common basis for liver disease in the
United States, having infected an estimated 3.9 million people in this country and an …

Hepatitis C virus (HCV) is the major cause of transfusion-acquired non-A, non-B hepatitis.
HCV is an enveloped positive-sense RNA virus which has been classified as a new genus …