The gut microbiome and hypertension

JA O'Donnell, T Zheng, G Meric… - Nature Reviews …, 2023 - nature.com
A large body of evidence has emerged in the past decade supporting a role for the gut
microbiome in the regulation of blood pressure. The field has moved from association to …

Multimodal interactions of drugs, natural compounds and pollutants with the gut microbiota

AE Lindell, M Zimmermann-Kogadeeva… - Nature Reviews …, 2022 - nature.com
The gut microbiota contributes to diverse aspects of host physiology, ranging from
immunomodulation to drug metabolism. Changes in the gut microbiota composition are …

[HTML][HTML] ABO genotype alters the gut microbiota by regulating GalNAc levels in pigs

H Yang, J Wu, X Huang, Y Zhou, Y Zhang, M Liu, Q Liu… - Nature, 2022 - nature.com
The composition of the intestinal microbiome varies considerably between individuals and is
correlated with health. Understanding the extent to which, and how, host genetics …

Combined effects of host genetics and diet on human gut microbiota and incident disease in a single population cohort

Y Qin, AS Havulinna, Y Liu, P Jousilahti, SC Ritchie… - Nature Genetics, 2022 - nature.com
Human genetic variation affects the gut microbiota through a complex combination of
environmental and host factors. Here we characterize genetic variations associated with …

Effect of host genetics on the gut microbiome in 7,738 participants of the Dutch Microbiome Project

EA Lopera-Maya, A Kurilshikov, A van der Graaf, S Hu… - Nature …, 2022 - nature.com
Host genetics are known to influence the gut microbiome, yet their role remains poorly
understood. To robustly characterize these effects, we performed a genome-wide …

Dysosmobacter welbionis is a newly isolated human commensal bacterium preventing diet-induced obesity and metabolic disorders in mice

T Le Roy, EM de Hase, M Van Hul, A Paquot… - Gut, 2022 - gut.bmj.com
Objective To investigate the abundance and the prevalence of Dysosmobacter welbionis
J115T, a novel butyrate-producing bacterium isolated from the human gut both in the …

Challenges and future directions for studying effects of host genetics on the gut microbiome

S Sanna, A Kurilshikov, A van der Graaf, J Fu… - Nature …, 2022 - nature.com
The human gut microbiome is a complex ecosystem that is involved in its host's metabolism,
immunity and health. Although interindividual variations in gut microbial composition are …

[HTML][HTML] Gut microbiota in various childhood disorders: Implication and indications

NK Saeed, M Al-Beltagi, AS Bediwy… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Gut microbiota has a significant role in gut development, maturation, and immune system
differentiation. It exerts considerable effects on the child's physical and mental development …

Examining the healthy human microbiome concept

R Joos, K Boucher, A Lavelle, M Arumugam… - Nature Reviews …, 2024 - nature.com
Human microbiomes are essential to health throughout the lifespan and are increasingly
recognized and studied for their roles in metabolic, immunological and neurological …