Organoids: The current status and biomedical applications

S Yang, H Hu, H Kung, R Zou, Y Dai, Y Hu… - MedComm, 2023 - Wiley Online Library
Organoids are three‐dimensional (3D) miniaturized versions of organs or tissues that are
derived from cells with stem potential and can self‐organize and differentiate into 3D cell …

The role of CCL3 in the pathogenesis of rheumatoid arthritis

YL Yang, XF Li, B Song, S Wu, YY Wu… - Rheumatology and …, 2023 - Springer
Rheumatoid arthritis (RA) is a chronic autoimmune disease of unexplained causes. Its
pathological features include synovial tissue hyperplasia, inflammatory cell infiltration in joint …

Organoids: development and applications in disease models, drug discovery, precision medicine, and regenerative medicine

Q Yao, S Cheng, Q Pan, J Yu, G Cao, L Li, H Cao - MedComm, 2024 - Wiley Online Library
Organoids are miniature, highly accurate representations of organs that capture the structure
and unique functions of specific organs. Although the field of organoids has experienced …

The immune landscape of papillary thyroid cancer in the context of autoimmune thyroiditis

F Pani, P Caria, Y Yasuda, M Makoto, S Mariotti… - Cancers, 2022 - mdpi.com
Simple Summary The association between papillary thyroid cancer and Hashimoto's
thyroiditis went through a long-standing human debate recently elucidated by the …

Patient-derived organoids: a game-changer in Personalized Cancer Medicine

MH Abbasian, N Sobhani, MM Sisakht… - Stem Cell Reviews and …, 2024 - Springer
Research on cancer therapies has benefited from predictive tools capable of simulating
treatment response and other disease characteristics in a personalized manner, in particular …

[HTML][HTML] Combined transcriptome and microbiome analysis reveals the thyrotoxic effects of PM2. 5 in female rats

X Dong, X Han, S Yao, Y Su, Z Luo, L Deng… - Ecotoxicology and …, 2024 - Elsevier
Pervasive environmental pollutants, specifically particulate matter (PM 2.5), possess the
potential to disrupt homeostasis of female thyroid hormone (TH). However, the precise …

Advances in Thyroid Organoids Research and Applications

K Song, Y Wang, Y Wang, W Yao, Y Tang… - Endocrine …, 2024 - Taylor & Francis
Introduction Organoids are three-dimensional cellular aggregates derived from stem cells or
primary tissues that can self-organize into organotypic structures and showcase the …

Plasma metabolomics reveals β-glucan improves muscle strength and exercise capacity in athletes

R Wang, X Wu, K Lin, S Guo, Y Hou, R Ma, Q Wang… - Metabolites, 2022 - mdpi.com
The present study aimed to assess the changes in muscle strength and plasma metabolites
in athletes with β-glucan supplementation. A total of 29 athletes who met the inclusion …

PARP1 inhibition enhances reactive oxygen species on gut microbiota

Y Zhuang, H Wang, J Ding, X Zhang… - Journal of Cellular …, 2022 - Wiley Online Library
Abstract Poly (ADP‐ribose) polymerase 1 (PARP1) plays a key role in genome stability by
modulating DNA‐damage responses. Activated by DNA interruptions through ultraviolet …

Iodide excess inhibits thyroid hormone synthesis pathway involving XBP1-mediated regulation

J Yu, S Shen, Y Yan, L Liu, R Luo, S Liu, Y Wu, Y Li… - Nutrients, 2023 - mdpi.com
Iodine is an essential micronutrient for producing thyroid hormone (TH); however, iodide
excess can lead to adverse thyroidal effects. Unfortunately, the lack of a proper in vitro …