[PDF][PDF] What can pharmacokinetic modelling do for you? Rational design and interpretation of clinical studies

FW Ojara, AN Kawuma, C Waitt - British Journal of Clinical …, 2024 - authorea.com
Integration of data, including patient and treatment characteristics, along with drug exposure
to optimize treatment has been possible for more than fifty years. 1 Quantitative …

A Guide for Implementing DPYD Genoty** for Systemic Fluoropyrimidines into Clinical Practice

TT Ho, DM Smith, CL Aquilante, EJ Cicali… - Clinical Pharmacology … - Wiley Online Library
The safety of systemic fluoropyrimidines (eg, 5‐fluorouracil, capecitabine) is impacted by
germline genetic variants in DPYD, which encodes the dihydropyrimidine dehydrogenase …