Genomic surveillance for antimicrobial resistance—a One Health perspective

SP Djordjevic, VM Jarocki, T Seemann… - Nature Reviews …, 2024‏ - nature.com
Antimicrobial resistance (AMR)—the ability of microorganisms to adapt and survive under
diverse chemical selection pressures—is influenced by complex interactions between …

[HTML][HTML] Antimicrobial resistance and its spread is a global threat

MM Aljeldah - Antibiotics, 2022‏ - mdpi.com
Antimicrobial resistance (AMR) is a challenge to human wellbeing the world over and is one
of the more serious public health concerns. AMR has the potential to emerge as a serious …

ResFinder–an open online resource for identification of antimicrobial resistance genes in next-generation sequencing data and prediction of phenotypes from …

AF Florensa, RS Kaas, PTLC Clausen… - Microbial …, 2022‏ - microbiologyresearch.org
Antimicrobial resistance (AMR) is one of the most important health threats globally. The
ability to accurately identify resistant bacterial isolates and the individual antimicrobial …

Minimizing treatment-induced emergence of antibiotic resistance in bacterial infections

M Stracy, O Snitser, I Yelin, Y Amer, M Parizade, R Katz… - Science, 2022‏ - science.org
Treatment of bacterial infections currently focuses on choosing an antibiotic that matches a
pathogen's susceptibility, with less attention paid to the risk that even susceptibility-matched …

ResFinder 4.0 for predictions of phenotypes from genotypes

V Bortolaia, RS Kaas, E Ruppe… - Journal of …, 2020‏ - academic.oup.com
Objectives WGS-based antimicrobial susceptibility testing (AST) is as reliable as phenotypic
AST for several antimicrobial/bacterial species combinations. However, routine use of WGS …

Sequencing-based methods and resources to study antimicrobial resistance

M Boolchandani, AW D'Souza, G Dantas - Nature Reviews Genetics, 2019‏ - nature.com
Antimicrobial resistance extracts high morbidity, mortality and economic costs yearly by
rendering bacteria immune to antibiotics. Identifying and understanding antimicrobial …

MEGARes and AMR++, v3. 0: an updated comprehensive database of antimicrobial resistance determinants and an improved software pipeline for classification using …

N Bonin, E Doster, H Worley, LJ Pinnell… - Nucleic acids …, 2023‏ - academic.oup.com
Antimicrobial resistance (AMR) is considered a critical threat to public health, and
genomic/metagenomic investigations featuring high-throughput analysis of sequence data …

Using genomics to track global antimicrobial resistance

RS Hendriksen, V Bortolaia, H Tate, GH Tyson… - Frontiers in public …, 2019‏ - frontiersin.org
The recent advancements in rapid and affordable DNA sequencing technologies have
revolutionized diagnostic microbiology and microbial surveillance. The availability of …

[HTML][HTML] Correlation between Phenotypic and In Silico Detection of Antimicrobial Resistance in Salmonella enterica in Canada Using Staramr

A Bharat, A Petkau, BP Avery, JC Chen, JP Folster… - Microorganisms, 2022‏ - mdpi.com
Whole genome sequencing (WGS) of Salmonella supports both molecular ty** and
detection of antimicrobial resistance (AMR). Here, we evaluated the correlation between …

Genome-based prediction of bacterial antibiotic resistance

M Su, SW Satola, TD Read - Journal of clinical microbiology, 2019‏ - journals.asm.org
Clinical microbiology has long relied on growing bacteria in culture to determine
antimicrobial susceptibility profiles, but the use of whole-genome sequencing for antibiotic …