Of wide interest for health is the relation existing between depression, a very common
psychological illness, accompanied by anxiety and reduced ability to concentrate, and adult …

For years, the biochemical processes that are triggered by harmful and non-harmful stimuli
at the central nervous system level have been extensively studied by the scientific …

Aim Adult neurogenesis occurs in two major niches in the brain: the subgranular zone of the
hippocampal formation and the ventricular‐subventricular zone. Neurogenesis in both …

Background Subcortical ischemic vascular dementia, one of the major subtypes of vascular
dementia, is characterized by lacunar infarcts and white matter lesions caused by chronic …

Environmental enrichment (EE) is a widely used paradigm for investigating the influence of
complex stimulations on brain and behavior. Here we examined whether pre-reproductive …

In the adult brain the neurogenesis is mainly restricted to two neurogenic regions: newly
generated neurons arise at the subventricular zone (SVZ) of the lateral ventricle and at the …

Bone morphogenetic proteins (BMPs) are growth factors that represent the largest subgroup
of signalling ligands of the transforming growth factor beta (TGF-β) superfamily. Their …

The PC3/Tis21/Btg2 and Btg1 genes are transcriptional cofactors belonging to the Btg/Tob
family, which regulate the development of several cell types, including neural precursors …

Epigenetics is one of the most rapidly expanding fields in biomedical research, and the
popularity of the high-throughput next-generation sequencing (NGS) highlights the …

Cerebellar granule neurons develop postnatally from cerebellar granule precursors (GCPs),
which are located in the external granule layer (EGL) where they massively proliferate …