The ability of articular cartilage to repair itself is limited because it lacks blood vessels,
nerves, and lymph tissue. Once damaged, it can lead to joint swelling and pain, accelerating …

Mesenchymal stem cells (MSCs) can be derived from various adult tissues with multipotent
and self‐renewal abilities. The characteristics of presenting no major ethical concerns …

In addition to being multi-potent, mesenchymal stem cells (MSCs) possess
immunomodulatory functions that have been investigated as potential treatments in various …

A large number of clinical trials have shown stem cell therapy to be a promising therapeutic
approach for the treatment of cardiovascular diseases. Since the first transplantation into …

Two major monocyte subsets, CD14+ CD16−(classical) and CD14+/dim
CD16+(nonclassical/intermediate), have been described. Each has different functions …

Rheumatoid arthritis (RA) is considered to be a degenerative and progressive autoimmune
disorder. Although several medicinal regimens are used to treat RA, potential adverse …

Brown and beige adipocytes contribute significantly to the regulation of whole body energy
expenditure and systemic metabolic homeostasis not exclusively by thermogenesis through …

Oxidative stress on transplanted bone marrow-derived mesenchymal stem cells (BMSCs)
during acute inflammation is a critical issue in cell therapies. N-acetyl-L cysteine (NAC) …

Objectives Synovial fibroblasts actively regulate the inflammatory infiltrate by communicating
with neighbouring endothelial cells (EC). Surprisingly, little is known about how the …

Chronic inflammation is associated with formation of ectopic fat deposits that might represent
damage-induced aberrant mesenchymal stem cell (MSC) differentiation. Such deposits are …