Bioinorganic chemistry of Alzheimer's disease
KP Kepp - Chemical reviews, 2012 - ACS Publications
Alzheimer's disease (AD) 1− 3 is the most common form of dementia (estimated∼ 50− 60%
of all cases), associated with loss of memory (in particular episodic memory), cognitive …
of all cases), associated with loss of memory (in particular episodic memory), cognitive …
Glutathione metabolism and Parkinson's disease
M Smeyne, RJ Smeyne - Free Radical Biology and Medicine, 2013 - Elsevier
It has been established that oxidative stress, defined as the condition in which the sum of
free radicals in a cell exceeds the antioxidant capacity of the cell, contributes to the …
free radicals in a cell exceeds the antioxidant capacity of the cell, contributes to the …
β-Caryophyllene suppresses ferroptosis induced by cerebral ischemia reperfusion via activation of the NRF2/HO-1 signaling pathway in MCAO/R rats
Q Hu, T Zuo, L Deng, S Chen, W Yu, S Liu, JD Liu… - Phytomedicine, 2022 - Elsevier
Background Ischemic stroke is a complex brain disease regulated by several cell death
processes, including apoptosis, autophagy, and ferroptosis. β-Caryophyllene (BCP), a …
processes, including apoptosis, autophagy, and ferroptosis. β-Caryophyllene (BCP), a …
Targeting chelatable iron as a therapeutic modality in Parkinson's disease
Aims: The pathophysiological role of iron in Parkinson's disease (PD) was assessed by a
chelation strategy aimed at reducing oxidative damage associated with regional iron …
chelation strategy aimed at reducing oxidative damage associated with regional iron …
Recent development of multifunctional agents as potential drug candidates for the treatment of Alzheimer's disease
N Guzior, A Wieckowska, D Panek… - Current medicinal …, 2015 - ingentaconnect.com
Alzheimer's disease (AD) is a complex and progressive neurodegenerative disorder. The
available therapy is limited to the symptomatic treatment and its efficacy remains …
available therapy is limited to the symptomatic treatment and its efficacy remains …
Brain iron metabolism and CNS diseases
A Thirupathi, YZ Chang - Brain Iron Metabolism and CNS Diseases, 2019 - Springer
Iron is the most abundant trace element in the human body. It is well known that iron is an
important component of hemoglobin involved in the transport of oxygen. As a component of …
important component of hemoglobin involved in the transport of oxygen. As a component of …
A review of soil NO transformation: associated processes and possible physiological significance on organisms
NO emissions from soils and ecosystems are of outstanding importance for atmospheric
chemistry. Here we review the current knowledge on processes involved in the formation …
chemistry. Here we review the current knowledge on processes involved in the formation …
Influence of trace elements on neurodegenerative diseases of the eye—the glaucoma model
Glaucoma is a heterogeneous group of chronic neurodegenerative disorders characterized
by a relatively selective, progressive damage to the retinal ganglion cells (RGCs) and their …
by a relatively selective, progressive damage to the retinal ganglion cells (RGCs) and their …
Medical treatment of dystonia
J Jankovic - Movement disorders, 2013 - Wiley Online Library
Medications such as anticholinergic drugs, dopamine modulators, baclofen, muscle
relaxants, and other pharmacologic agents have been used for a long time to treat dystonia …
relaxants, and other pharmacologic agents have been used for a long time to treat dystonia …
Relationships between disease progression and serum levels of lipid, urate, creatinine and ferritin in Japanese patients with amyotrophic lateral sclerosis: a cross …
K Ikeda, T Hirayama, T Takazawa, K Kawabe… - Internal …, 2012 - jstage.jst.go.jp
Objective Previous studies have reported distinct serological profiles of lipid, urate and
ferritin in Western patients with amyotrophic lateral sclerosis (ALS). We aimed to examine …
ferritin in Western patients with amyotrophic lateral sclerosis (ALS). We aimed to examine …