Microneedle-based insulin transdermal delivery system: current status and translation challenges

J Zhao, G Xu, X Yao, H Zhou, B Lyu, S Pei… - Drug Delivery and …, 2022 - Springer
Diabetes mellitus is a metabolic disease manifested by hyperglycemia. For patients with
type 1 and advanced type 2 diabetes mellitus, insulin therapy is essential. Subcutaneous …

[HTML][HTML] Biocompatibility of su-8 and its biomedical device applications

Z Chen, JB Lee - Micromachines, 2021 - mdpi.com
SU-8 is an epoxy-based, negative-tone photoresist that has been extensively utilized to
fabricate myriads of devices including biomedical devices in the recent years. This paper …

Fabrication of sharp silicon hollow microneedles by deep-reactive ion etching towards minimally invasive diagnostics

Y Li, H Zhang, R Yang, Y Laffitte, U Schmill… - Microsystems & …, 2019 - nature.com
Microneedle technologies have the potential for expanding the capabilities of wearable
health monitoring from physiology to biochemistry. This paper presents the fabrication of …

Review of polymer MEMS micromachining

BJ Kim, E Meng - Journal of Micromechanics and …, 2015 - iopscience.iop.org
The development of polymer micromachining technologies that complement traditional
silicon approaches has enabled the broadening of microelectromechanical systems (MEMS) …

Diagnostic and drug release systems based on microneedle arrays in breast cancer therapy

S Khan, A Hasan, F Attar, MMN Babadaei… - Journal of Controlled …, 2021 - Elsevier
Microneedle arrays have recently received much attention as cancer detection and
treatment platforms, because invasive injections and detection of the biopsy are not needed …

Considerations in the use of microneedles: pain, convenience, anxiety and safety

HR Jeong, HS Lee, IJ Choi, JH Park - Journal of drug targeting, 2017 - Taylor & Francis
Transdermal delivery using microneedles is gaining increasing attention from
pharmaceutical and cosmetic companies as one of the promising drug delivery methods …

A review on surface stress-based miniaturized piezoresistive SU-8 polymeric cantilever sensors

R Mathew, A Ravi Sankar - Nano-micro letters, 2018 - Springer
In the last decade, microelectromechanical systems (MEMS) SU-8 polymeric cantilevers with
piezoresistive readout combined with the advances in molecular recognition techniques …

Drug coated microneedles for minimally-invasive treatment of oral carcinomas: development and in vitro evaluation

Y Ma, SE Boese, Z Luo, N Nitin, HS Gill - Biomedical microdevices, 2015 - Springer
Abstract Treatment of recurring oral cancers is challenging as common surgical approaches
are not feasible for these patients. In addition, these patients do not respond well to systemic …

A flexible three-dimensional electrode mesh: An enabling technology for wireless brain–computer interface prostheses

Z **ang, J Liu, C Lee - Microsystems & Nanoengineering, 2016 - nature.com
The neural interface is a key component in wireless brain–computer prostheses. In this
study, we demonstrate that a unique three-dimensional (3D) microneedle electrode on a …

[HTML][HTML] Microneedle-Based Glucose Sensor Platform: From Vitro to Wearable Point-of-Care Testing Systems

J Ju, L Li, S Regmi, X Zhang, S Tang - Biosensors, 2022 - mdpi.com
Significant advanced have recently been made in exploiting microneedle-based (MN-
based) diabetes devices for minimally invasive wearable biosensors and for continuous …