Physical exercise (PE) improves physical performance, mental status, general health, and
well-being. It does so by affecting many mechanisms at the cellular and molecular level. PE …

For cognitive processes to function well, it is essential that the brain is optimally supplied
with oxygen and blood. In recent years, evidence has emerged suggesting that cerebral …

Physical exercise can improve brain function and delay neurodegeneration; however, the
initial signal from muscle to brain is unknown. Here we show that the lactate receptor …

The demographic change in industrial countries, with increasingly sedentary lifestyles, has a
negative impact on mental health. Normal and pathological aging leads to cognitive deficits …

In general, it is well recognized that both acute physical exercises and regular physical
training influence brain plasticity and cognitive functions positively. However, growing …

The health benefits of resistance exercises are well established; however, the effects of
resistance training on cognition are not as well understood. The purpose of this meta …

Background There is mounting evidence that regular physical activity is an important
prerequisite for healthy cognitive aging. Consequently, the finding that almost one-third of …

Adult hippocampal neurogenesis is important for learning and memory and is altered early
in Alzheimer's disease. As hippocampal neurogenesis is modulated by the circulatory …

Senile dementia, also known as dementia, is the mental deterioration which is associated
with aging. It is characterized by a decrease in cognitive abilities, inability to concentrate …

Exercise has systemic health benefits in people, in part, through improving whole body
insulin sensitivity. The brain is an insulin-sensitive organ that is often underdiscussed …