Global measles elimination

WJ Moss, DE Griffin - Nature Reviews Microbiology, 2006 - nature.com
Measles remains a leading vaccine-preventable cause of child mortality worldwide,
particularly in sub-Saharan Africa where almost half of the estimated 454,000 measles …

The immune response in measles: virus control, clearance and protective immunity

DE Griffin - Viruses, 2016 - mdpi.com
Measles is an acute systemic viral infection with immune system interactions that play
essential roles in multiple stages of infection and disease. Measles virus (MeV) infection …

Measles virus‐induced suppression of immune responses

DE Griffin - Immunological reviews, 2010 - Wiley Online Library
Measles is an important cause of child mortality that has a seemingly paradoxical interaction
with the immune system. In most individuals, the immune response is successful in …

A ferret model of canine distemper virus virulence and immunosuppression

V Von Messling, C Springfeld, P Devaux… - Journal of …, 2003 - Am Soc Microbiol
Canine distemper virus (CDV) infects many carnivores, including ferrets and dogs, and is the
member of the Morbillivirus genus most easily amenable to experimentation in a …

Tropism illuminated: lymphocyte-based pathways blazed by lethal morbillivirus through the host immune system

V Von Messling, D Milosevic… - Proceedings of the …, 2004 - National Acad Sciences
The immunosuppressive properties of morbilliviruses including measles and canine
distemper virus (CDV) are well known, but the host cells supporting infection are poorly …

Measles virus, immune control, and persistence

DE Griffin, WH Lin, CH Pan - FEMS microbiology reviews, 2012 - academic.oup.com
Measles remains one of the most important causes of child morbidity and mortality
worldwide with the greatest burden in the youngest children. Most acute measles deaths are …

Phocine distemper virus: current knowledge and future directions

PJ Duignan, MF Van Bressem, JD Baker, M Barbieri… - Viruses, 2014 - mdpi.com
Phocine distemper virus (PDV) was first recognized in 1988 following a massive epidemic in
harbor and grey seals in north-western Europe. Since then, the epidemiology of infection in …

Minimal change disease: a “two-hit” podocyte immune disorder?

M Shimada, C Araya, C Rivard, T Ishimoto… - Pediatric …, 2011 - Springer
Minimal change disease (MCD) is the most common nephrotic syndrome in children and is
commonly thought to be a T-cell disorder mediated by a circulating factor that alters …

Measles virus persistence and its consequences

DE Griffin - Current opinion in virology, 2020 - Elsevier
Highlights•In immunocompromised patients failure of measles virus clearance may lead to
progressive lung or nervous system disease.•Children infected at a young age may develop …

Attenuation of V-or C-defective measles viruses: infection control by the inflammatory and interferon responses of rhesus monkeys

P Devaux, G Hodge, MB McChesney… - Journal of …, 2008 - Am Soc Microbiol
Patients recruited in virus-based cancer clinical trials and immunocompromised individuals
in need of vaccination would profit from viral strains with defined attenuation mechanisms …