Global measles elimination
WJ Moss, DE Griffin - Nature Reviews Microbiology, 2006 - nature.com
Measles remains a leading vaccine-preventable cause of child mortality worldwide,
particularly in sub-Saharan Africa where almost half of the estimated 454,000 measles …
particularly in sub-Saharan Africa where almost half of the estimated 454,000 measles …
The immune response in measles: virus control, clearance and protective immunity
DE Griffin - Viruses, 2016 - mdpi.com
Measles is an acute systemic viral infection with immune system interactions that play
essential roles in multiple stages of infection and disease. Measles virus (MeV) infection …
essential roles in multiple stages of infection and disease. Measles virus (MeV) infection …
Measles virus‐induced suppression of immune responses
DE Griffin - Immunological reviews, 2010 - Wiley Online Library
Measles is an important cause of child mortality that has a seemingly paradoxical interaction
with the immune system. In most individuals, the immune response is successful in …
with the immune system. In most individuals, the immune response is successful in …
A ferret model of canine distemper virus virulence and immunosuppression
V Von Messling, C Springfeld, P Devaux… - Journal of …, 2003 - Am Soc Microbiol
Canine distemper virus (CDV) infects many carnivores, including ferrets and dogs, and is the
member of the Morbillivirus genus most easily amenable to experimentation in a …
member of the Morbillivirus genus most easily amenable to experimentation in a …
Tropism illuminated: lymphocyte-based pathways blazed by lethal morbillivirus through the host immune system
V Von Messling, D Milosevic… - Proceedings of the …, 2004 - National Acad Sciences
The immunosuppressive properties of morbilliviruses including measles and canine
distemper virus (CDV) are well known, but the host cells supporting infection are poorly …
distemper virus (CDV) are well known, but the host cells supporting infection are poorly …
Measles virus, immune control, and persistence
Measles remains one of the most important causes of child morbidity and mortality
worldwide with the greatest burden in the youngest children. Most acute measles deaths are …
worldwide with the greatest burden in the youngest children. Most acute measles deaths are …
Phocine distemper virus: current knowledge and future directions
PJ Duignan, MF Van Bressem, JD Baker, M Barbieri… - Viruses, 2014 - mdpi.com
Phocine distemper virus (PDV) was first recognized in 1988 following a massive epidemic in
harbor and grey seals in north-western Europe. Since then, the epidemiology of infection in …
harbor and grey seals in north-western Europe. Since then, the epidemiology of infection in …
Minimal change disease: a “two-hit” podocyte immune disorder?
M Shimada, C Araya, C Rivard, T Ishimoto… - Pediatric …, 2011 - Springer
Minimal change disease (MCD) is the most common nephrotic syndrome in children and is
commonly thought to be a T-cell disorder mediated by a circulating factor that alters …
commonly thought to be a T-cell disorder mediated by a circulating factor that alters …
Measles virus persistence and its consequences
DE Griffin - Current opinion in virology, 2020 - Elsevier
Highlights•In immunocompromised patients failure of measles virus clearance may lead to
progressive lung or nervous system disease.•Children infected at a young age may develop …
progressive lung or nervous system disease.•Children infected at a young age may develop …
Attenuation of V-or C-defective measles viruses: infection control by the inflammatory and interferon responses of rhesus monkeys
P Devaux, G Hodge, MB McChesney… - Journal of …, 2008 - Am Soc Microbiol
Patients recruited in virus-based cancer clinical trials and immunocompromised individuals
in need of vaccination would profit from viral strains with defined attenuation mechanisms …
in need of vaccination would profit from viral strains with defined attenuation mechanisms …