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The amyloid beta peptide: a chemist's perspective. Role in Alzheimer's and fibrillization
IW Hamley - Chemical reviews, 2012 - ACS Publications
This review is concerned with the role of fibrillization of the amyloid β (Aβ)-peptide in
Alzheimer's disease (AD). The perspective is that of a physical chemist, and one aim is to …
Alzheimer's disease (AD). The perspective is that of a physical chemist, and one aim is to …
Peptide amyloids in the origin of life
How life can emerge from non-living matter is one of the fundamental mysteries of the
universe. A bottom-up approach to this problem focuses on the potential chemical …
universe. A bottom-up approach to this problem focuses on the potential chemical …
Hydrogelation and self-assembly of Fmoc-tripeptides: unexpected influence of sequence on self-assembled fibril structure, and hydrogel modulus and anisotropy
G Cheng, V Castelletto, CM Moulton, GE Newby… - Langmuir, 2010 - ACS Publications
The self-assembly and hydrogelation properties of two Fmoc-tripeptides [Fmoc= N-(fluorenyl-
9-methoxycarbonyl)] are investigated, in borate buffer and other basic solutions. A …
9-methoxycarbonyl)] are investigated, in borate buffer and other basic solutions. A …
Phenylalanine-based fibrillar systems
Phenylketonuria (PKU) is an inborn metabolic disorder characterized by excess
accumulation of phenylalanine (Phe) and its fibril formation, resulting in progressive …
accumulation of phenylalanine (Phe) and its fibril formation, resulting in progressive …
In vitro digestion and stability under environmental stresses of ovotransferrin nanofibrils
Z Wei, Q Huang - Food Hydrocolloids, 2020 - Elsevier
The objectives of this study were to investigate in vitro digestion and stability under
environmental stresses of ovotransferrin (OVT) nanofibrils. Gastrointestinal digestion of OVT …
environmental stresses of ovotransferrin (OVT) nanofibrils. Gastrointestinal digestion of OVT …
Formation of hybrid hydrogels consisting of tripeptide and different silver nanoparticle-capped ligands: modulation of the mechanical strength of gel phase materials
An N-terminally Boc (tert-butyloxycarbonyl) group-protected synthetic tripeptide (Boc-Phe-
Phe-Ala–OH) has been found to form a translucent hydrogel in basic aqueous medium. This …
Phe-Ala–OH) has been found to form a translucent hydrogel in basic aqueous medium. This …
Supramolecular antiparallel β-sheet formation by tetrapeptides based on amyloid sequence
Self-assembly of short peptides has emerged as an interesting research field for a wide
range of applications. Recently, several truncated fragments of long-chain peptides or …
range of applications. Recently, several truncated fragments of long-chain peptides or …
Modified dipeptide-based nanoparticles: vehicles for targeted tumor drug delivery
Aim: Different nanoparticles have been investigated to deliver chemotherapeutic agents, but
complex synthesis procedures and biocompatibility issues raise concerns in develo** …
complex synthesis procedures and biocompatibility issues raise concerns in develo** …
Supramolecular Gelation Based on Native Amino Acid Tyrosine and Its Charge-Transfer Complex Formation
Self-assembly of amino acids and short-peptide derivatives attracted significant curiosity
worldwide due to their unique self-assembly process and wide variety of applications. Amino …
worldwide due to their unique self-assembly process and wide variety of applications. Amino …
Quantifying L-ascorbic acid-driven inhibitory effect on amyloid fibrillation
Ascorbic acid, which is widely used as a therapeutic agent for various disorders (eg chronic
diseases and cancers), has potential therapeutic roles for neurodegenerative disease such …
diseases and cancers), has potential therapeutic roles for neurodegenerative disease such …