The amyloid beta peptide: a chemist's perspective. Role in Alzheimer's and fibrillization

IW Hamley - Chemical reviews, 2012 - ACS Publications
This review is concerned with the role of fibrillization of the amyloid β (Aβ)-peptide in
Alzheimer's disease (AD). The perspective is that of a physical chemist, and one aim is to …

Peptide amyloids in the origin of life

J Greenwald, W Kwiatkowski, R Riek - Journal of molecular biology, 2018 - Elsevier
How life can emerge from non-living matter is one of the fundamental mysteries of the
universe. A bottom-up approach to this problem focuses on the potential chemical …

Hydrogelation and self-assembly of Fmoc-tripeptides: unexpected influence of sequence on self-assembled fibril structure, and hydrogel modulus and anisotropy

G Cheng, V Castelletto, CM Moulton, GE Newby… - Langmuir, 2010 - ACS Publications
The self-assembly and hydrogelation properties of two Fmoc-tripeptides [Fmoc= N-(fluorenyl-
9-methoxycarbonyl)] are investigated, in borate buffer and other basic solutions. A …

Phenylalanine-based fibrillar systems

S Kuila, S Dey, P Singh, A Shrivastava… - Chemical …, 2023 - pubs.rsc.org
Phenylketonuria (PKU) is an inborn metabolic disorder characterized by excess
accumulation of phenylalanine (Phe) and its fibril formation, resulting in progressive …

In vitro digestion and stability under environmental stresses of ovotransferrin nanofibrils

Z Wei, Q Huang - Food Hydrocolloids, 2020 - Elsevier
The objectives of this study were to investigate in vitro digestion and stability under
environmental stresses of ovotransferrin (OVT) nanofibrils. Gastrointestinal digestion of OVT …

Formation of hybrid hydrogels consisting of tripeptide and different silver nanoparticle-capped ligands: modulation of the mechanical strength of gel phase materials

J Nanda, B Adhikari, S Basak… - The Journal of Physical …, 2012 - ACS Publications
An N-terminally Boc (tert-butyloxycarbonyl) group-protected synthetic tripeptide (Boc-Phe-
Phe-Ala–OH) has been found to form a translucent hydrogel in basic aqueous medium. This …

Supramolecular antiparallel β-sheet formation by tetrapeptides based on amyloid sequence

S Misra, P Singh, RN Mahata, P Brandão… - The Journal of …, 2021 - ACS Publications
Self-assembly of short peptides has emerged as an interesting research field for a wide
range of applications. Recently, several truncated fragments of long-chain peptides or …

Modified dipeptide-based nanoparticles: vehicles for targeted tumor drug delivery

JJ Panda, A Kaul, S Kumar, S Alam, AK Mishra… - …, 2013 - Taylor & Francis
Aim: Different nanoparticles have been investigated to deliver chemotherapeutic agents, but
complex synthesis procedures and biocompatibility issues raise concerns in develo** …

Supramolecular Gelation Based on Native Amino Acid Tyrosine and Its Charge-Transfer Complex Formation

P Singh, MS Yadav, S Kuila, AK Paul, D Ray, S Misra… - Langmuir, 2025 - ACS Publications
Self-assembly of amino acids and short-peptide derivatives attracted significant curiosity
worldwide due to their unique self-assembly process and wide variety of applications. Amino …

Quantifying L-ascorbic acid-driven inhibitory effect on amyloid fibrillation

W Lee, I Kim, SW Lee, H Lee, G Lee, S Kim… - Macromolecular …, 2016 - Springer
Ascorbic acid, which is widely used as a therapeutic agent for various disorders (eg chronic
diseases and cancers), has potential therapeutic roles for neurodegenerative disease such …