Bioerodable PLGA-based microparticles for producing sustained-release drug formulations and strategies for improving drug loading

FY Han, KJ Thurecht, AK Whittaker… - Frontiers in …, 2016 - frontiersin.org
Poly (lactic-co-glycolic acid)(PLGA) is the most widely used biomaterial for
microencapsulation and prolonged delivery of therapeutic drugs, proteins and antigens …

Tailoring porous silicon for biomedical applications: from drug delivery to cancer immunotherapy

W Li, Z Liu, F Fontana, Y Ding, D Liu… - Advanced …, 2018 - Wiley Online Library
In the past two decades, porous silicon (PSi) has attracted increasing attention for its
potential biomedical applications. With its controllable geometry, tunable nanoporous …

The potential use of novel chitosan-coated deformable liposomes in an ocular drug delivery system

H Chen, H Pan, P Li, H Wang, X Wang, W Pan… - Colloids and surfaces B …, 2016 - Elsevier
In this study, novel chitosan-coated deformable liposomes (DL-CS) were proposed as an
ocular drug delivery system to prolong pre-corneal retention, and improve transcorneal …

Porous silicon for drug delivery applications and theranostics: recent advances, critical review and perspectives

T Kumeria, SJP McInnes, S Maher… - Expert opinion on drug …, 2017 - Taylor & Francis
Introduction: Porous silicon (pSi) engineered by electrochemical etching has been used as a
drug delivery vehicle to address the intrinsic limitations of traditional therapeutics …

[HTML][HTML] Biodegradable microspheres come into sight: A promising biomaterial for delivering drug to the posterior segment of the eyeball

R Xue, H Wu, S Li, N Pu, D Wei, N Zhao, Y Cui, H Li… - Materials Today Bio, 2024 - Elsevier
Posterior segment disease acts as a major cause of irreversible visual impairments.
Successful treatment of posterior segment disease requires the efficient delivery of …

Multifunctional carboxymethyl chitosan derivatives-layered double hydroxide hybrid nanocomposites for efficient drug delivery to the posterior segment of the eye

Y Wang, L Zhou, L Fang, F Cao - Acta biomaterialia, 2020 - Elsevier
Efficient ocular drug delivery to the posterior segment of the eye by topical administration is
a great challenge to pharmacologists. To explore drug delivery system of organic-inorganic …

Chitosan derivatives as effective nanocarriers for ocular release of timolol drug

PI Siafaka, A Titopoulou, EN Koukaras… - International journal of …, 2015 - Elsevier
The aim of the present study was to evaluate the effectiveness of neat chitosan (CS) and its
derivatives with succinic anhydride (CSUC) and 2-carboxybenzaldehyde (CBCS) as …

Non-invasive strategies for targeting the posterior segment of eye

A Madni, MA Rahem, N Tahir, M Sarfraz, A Jabar… - International journal of …, 2017 - Elsevier
The safe and effective treatment of eye diseases has been remained a global myth. Several
advancements have been done and various drug delivery and treatment techniques have …

Adaptive Cavitation Ultrasonication for Large-Scale Preparation of Porous Silicon Nanoparticles

J Lee, HJ Um, MJ Sailor, J Kim, H Jeong… - ACS Applied Nano …, 2024 - ACS Publications
Porous silicon nanoparticles (pSiNPs) are of increased interest for use in drug delivery
systems, as catalysts, and as biomedical imaging agents. The most common synthesis of …

Insulin-loaded PLGA microspheres for glucose-responsive release

JZ Wu, GR Williams, HY Li, DX Wang, SD Li… - Drug delivery, 2017 - Taylor & Francis
Porous poly (lactic-co-glycolic acid)(PLGA) microspheres were prepared, loaded with
insulin, and then coated in poly (vinyl alcohol)(PVA) and a novel boronic acid-containing …