[HTML][HTML] Therapeutic application of quercetin in aging-related diseases: SIRT1 as a potential mechanism

Z Cui, X Zhao, FK Amevor, X Du, Y Wang, D Li… - Frontiers in …, 2022 - frontiersin.org
Quercetin, a naturally non-toxic flavonoid within the safe dose range with antioxidant, anti-
apoptotic and anti-inflammatory properties, plays an important role in the treatment of aging …

[HTML][HTML] Vascular cognitive impairment (VCI)

T Rundek, M Tolea, T Ariko, EA Fagerli, CJ Camargo - Neurotherapeutics, 2022 - Elsevier
Vascular cognitive impairment (VCI) is predominately caused by vascular risk factors and
cerebrovascular disease. VCI includes a broad spectrum of cognitive disorders, from mild …

Biomarker changes during 20 years preceding Alzheimer's disease

J Jia, Y Ning, M Chen, S Wang, H Yang… - … England Journal of …, 2024 - Mass Medical Soc
Background Biomarker changes that occur in the period between normal cognition and the
diagnosis of sporadic Alzheimer's disease have not been extensively investigated in …

Adiponectin: structure, physiological functions, role in diseases, and effects of nutrition

K Khoramipour, K Chamari, AA Hekmatikar, A Ziyaiyan… - Nutrients, 2021 - mdpi.com
Adiponectin (a protein consisting of 244 amino acids and characterized by a molecular
weight of 28 kDa) is a cytokine that is secreted from adipose tissues (adipokine). Available …

The prevalence of dementia: a systematic review and meta-analysis

Q Cao, CC Tan, W Xu, H Hu, XP Cao… - Journal of …, 2020 - content.iospress.com
Dementia is a severe neurodegenerative disorder and it can be categorized into several
subtypes by different pathogenic causes. We sought to comprehensively analyzed the …

[HTML][HTML] Emerging concepts in vascular dementia: a review

SC Bir, MW Khan, V Javalkar, EG Toledo… - Journal of Stroke and …, 2021 - Elsevier
Abstract Objective Vascular dementia (VaD) is the second most common cause of dementia
and a major health concern worldwide. A comprehensive review on VaD is warranted for …

Prevalence, risk factors, and management of dementia and mild cognitive impairment in adults aged 60 years or older in China: a cross-sectional study

L Jia, Y Du, L Chu, Z Zhang, F Li, D Lyu, Y Li… - The Lancet public …, 2020 - thelancet.com
Background China has a large population of older people, but has not yet undertaken a
comprehensive study on the prevalence, risk factors, and management of both dementia …

Epidemiology of vascular dementia: nosology in a time of epiomics

FJ Wolters, MA Ikram - Arteriosclerosis, thrombosis, and vascular …, 2019 - ahajournals.org
The notion of what qualifies as vascular dementia has varied greatly since the first mention
of dementia after apoplexy in ancient literature. Current insight points towards a …

A comparative analysis of machine learning algorithms to predict Alzheimer's disease

M Bari Antor, AHMS Jamil, M Mamtaz… - Journal of …, 2021 - Wiley Online Library
Alzheimer's disease has been one of the major concerns recently. Around 45 million people
are suffering from this disease. Alzheimer's is a degenerative brain disease with an …

Defeating Alzheimer's disease and other dementias: a priority for European science and society

B Winblad, P Amouyel, S Andrieu, C Ballard… - The Lancet …, 2016 - thelancet.com
Executive summary Alzheimer's disease (AD) is the leading cause of dementia, and
because the primary risk factor for AD is old age, the prevalence of the disease is increasing …