Astrocyte-neuron metabolic cooperation shapes brain activity
G Bonvento, JP Bolaños - Cell metabolism, 2021 - cell.com
The brain has almost no energy reserve, but its activity coordinates organismal function, a
burden that requires precise coupling between neurotransmission and energy metabolism …
burden that requires precise coupling between neurotransmission and energy metabolism …
Lactate in the brain: from metabolic end-product to signalling molecule
PJ Magistretti, I Allaman - Nature reviews neuroscience, 2018 - nature.com
Lactate in the brain has long been associated with ischaemia; however, more recent
evidence shows that it can be found there under physiological conditions. In the brain …
evidence shows that it can be found there under physiological conditions. In the brain …
[HTML][HTML] Global minimum estimates of children affected by COVID-19-associated orphanhood and deaths of caregivers: a modelling study
Background The COVID-19 pandemic priorities have focused on prevention, detection, and
response. Beyond morbidity and mortality, pandemics carry secondary impacts, such as …
response. Beyond morbidity and mortality, pandemics carry secondary impacts, such as …
Brain glucose metabolism: integration of energetics with function
GA Dienel - Physiological reviews, 2019 - journals.physiology.org
Glucose is the long-established, obligatory fuel for brain that fulfills many critical functions,
including ATP production, oxidative stress management, and synthesis of neurotransmitters …
including ATP production, oxidative stress management, and synthesis of neurotransmitters …
Astrocyte function from information processing to cognition and cognitive impairment
Astrocytes serve important roles that affect recruitment and function of neurons at the local
and network levels. Here we review the contributions of astrocyte signaling to synaptic …
and network levels. Here we review the contributions of astrocyte signaling to synaptic …
Extant timetrees are consistent with a myriad of diversification histories
Time-calibrated phylogenies of extant species (referred to here as 'extant timetrees') are
widely used for estimating diversification dynamics. However, there has been considerable …
widely used for estimating diversification dynamics. However, there has been considerable …
Astrocytes as key regulators of brain energy metabolism: new therapeutic perspectives
Astrocytes play key roles in the regulation of brain energy metabolism, which has a major
impact on brain functions, including memory, neuroprotection, resistance to oxidative stress …
impact on brain functions, including memory, neuroprotection, resistance to oxidative stress …
[HTML][HTML] Astrocytic activation generates de novo neuronal potentiation and memory enhancement
Astrocytes respond to neuronal activity and were shown to be necessary for plasticity and
memory. To test whether astrocytic activity is also sufficient to generate synaptic potentiation …
memory. To test whether astrocytic activity is also sufficient to generate synaptic potentiation …
Conceptual and empirical bridges between micro-and macroevolution
Explaining broad molecular, phenotypic and species biodiversity patterns necessitates a
unifying framework spanning multiple evolutionary scales. Here we argue that although …
unifying framework spanning multiple evolutionary scales. Here we argue that although …
Astrocytes contribute to remote memory formation by modulating hippocampal–cortical communication during learning
A Kol, A Adamsky, M Groysman, T Kreisel… - Nature …, 2020 - nature.com
Remote memories depend on coordinated activity in the hippocampus and frontal cortices,
but the timeline of these interactions is debated. Astrocytes sense and modify neuronal …
but the timeline of these interactions is debated. Astrocytes sense and modify neuronal …