Short-chain fatty-acid-producing bacteria: key components of the human gut microbiota

W Fusco, MB Lorenzo, M Cintoni, S Porcari… - Nutrients, 2023 - mdpi.com
Short-chain fatty acids (SCFAs) play a key role in health and disease, as they regulate gut
homeostasis and their deficiency is involved in the pathogenesis of several disorders …

Gut microbial metabolites in obesity, NAFLD and T2DM

EE Canfora, RCR Meex, K Venema… - Nature Reviews …, 2019 - nature.com
Evidence is accumulating that the gut microbiome is involved in the aetiology of obesity and
obesity-related complications such as nonalcoholic fatty liver disease (NAFLD), insulin …

[HTML][HTML] Free fatty acid receptors in health and disease

I Kimura, A Ichimura, R Ohue-Kitano… - Physiological …, 2019 - journals.physiology.org
Fatty acids are metabolized and synthesized as energy substrates during biological
responses. Long-and medium-chain fatty acids derived mainly from dietary triglycerides, and …

The short-chain fatty acid acetate in body weight control and insulin sensitivity

MA González Hernández, EE Canfora, JWE Jocken… - Nutrients, 2019 - mdpi.com
The interplay of gut microbiota, host metabolism, and metabolic health has gained increased
attention. Gut microbiota may play a regulatory role in gastrointestinal health, substrate …

Metabolites as regulators of insulin sensitivity and metabolism

Q Yang, A Vijayakumar, BB Kahn - Nature reviews Molecular cell …, 2018 - nature.com
The cause of insulin resistance in obesity and type 2 diabetes mellitus (T2DM) is not limited
to impaired insulin signalling but also involves the complex interplay of multiple metabolic …

Intestinal microbiota-derived short chain fatty acids in host health and disease

J Cong, P Zhou, R Zhang - Nutrients, 2022 - mdpi.com
Intestinal microbiota has its role as an important component of human physiology. It
produces metabolites that module key functions to establish a symbiotic crosstalk with their …

The protective role of butyrate against obesity and obesity-related diseases

S Coppola, C Avagliano, A Calignano, R Berni Canani - Molecules, 2021 - mdpi.com
Worldwide obesity is a public health concern that has reached pandemic levels. Obesity is
the major predisposing factor to comorbidities, including type 2 diabetes, cardiovascular …

[HTML][HTML] Functions of gut microbiota metabolites, current status and future perspectives

J Liu, Y Tan, H Cheng, D Zhang, W Feng… - Aging and …, 2022 - ncbi.nlm.nih.gov
Gut microbiota, a collection of microorganisms that live within gastrointestinal tract, provides
crucial signaling metabolites for the physiological of hosts. In healthy state, gut microbiota …

Intestinal Cetobacterium and acetate modify glucose homeostasis via parasympathetic activation in zebrafish

A Wang, Z Zhang, Q Ding, Y Yang, J Bindelle… - Gut …, 2021 - Taylor & Francis
The capability of carbohydrate utilization in fish is limited compared to mammals. It has
scientific and practical significance to improve the ability of fish to use carbohydrates. The …

Short chain fatty acids in human gut and metabolic health

EE Blaak, EE Canfora, S Theis, G Frost… - Beneficial …, 2020 - wageningenacademic.com
Evidence is accumulating that short chain fatty acids (SCFA) play an important role in the
maintenance of gut and metabolic health. The SCFA acetate, propionate and butyrate are …