Abstract The Wright–Fisher family of diffusion processes is a widely used class of
evolutionary models. However, simulation is difficult because there is no known closed-form …

Our understanding of the genetic basis of human adaptation is biased toward loci of large
pheno-typic effect. Genome wide association studies (GWAS) now enable the study of …

No environment is constant over time, and environmental fluctuations impact the outcome of
evolutionary dynamics. Survival of a population not adapted to some environmental …

The effects of selection on variability at linked sites have an important influence on levels
and patterns of within-population variation across the genome. Most theoretical models of …

Using biological fertilizers and pesticides based on beneficial soil microbes in order to
reduce mineral fertilizers and chemical pesticides in conventional agriculture is still a matter …

A strong reduction in diversity around a specific locus is often interpreted as a recent rapid
fixation of a positively selected allele, a phenomenon called a selective sweep. Rapid …

Historically Plasmodium falciparum has followed a pattern of drug resistance first appearing
in low-transmission settings before spreading to high-transmission settings. Several features …

In finite populations, an allele disappears or reaches fixation due to two main forces,
selection and drift. Selection is generally thought to accelerate the process: a selected …

Pigeonpea (Cajanus cajan) has gained worldwide attention among forage legumes due to
its important role in animal nutrition, as well as its resilience to drought and high …

A central aim of population genetics is the inference of the evolutionary history of a
population. To this end, the underlying process can be represented by a model of the …