[HTML][HTML] Metabolic cycles and signals for insulin secretion
In this review, we focus on recent developments in our understanding of nutrient-induced
insulin secretion that challenge a key aspect of the" canonical" model, in which an oxidative …
insulin secretion that challenge a key aspect of the" canonical" model, in which an oxidative …
Cinnamaldehyde in diabetes: A review of pharmacology, pharmacokinetics and safety
R Zhu, H Liu, C Liu, L Wang, R Ma, B Chen, L Li… - Pharmacological …, 2017 - Elsevier
Cinnamaldehyde, one of the active components derived from Cinnamon, has been used as
a natural flavorant and fragrance agent in kitchen and industry. Emerging studies have been …
a natural flavorant and fragrance agent in kitchen and industry. Emerging studies have been …
MicroRNA-210 controls mitochondrial metabolism and protects heart function in myocardial infarction
Background: Ischemic heart disease remains a leading cause of death worldwide. In this
study, we test the hypothesis that microRNA-210 protects the heart from myocardial …
study, we test the hypothesis that microRNA-210 protects the heart from myocardial …
[HTML][HTML] Glycerol-3-phosphate biosynthesis regenerates cytosolic NAD+ to alleviate mitochondrial disease
Electron transport chain (ETC) dysfunction or hypoxia causes toxic NADH accumulation.
How cells regenerate NAD+ under such conditions remains elusive. Here, integrating …
How cells regenerate NAD+ under such conditions remains elusive. Here, integrating …
The photorespiratory metabolite 2-phosphoglycolate regulates photosynthesis and starch accumulation in Arabidopsis
Abstract The Calvin-Benson cycle and its photorespiratory repair shunt are in charge of
nearly all biological CO2 fixation on Earth. They interact functionally and via shared carbon …
nearly all biological CO2 fixation on Earth. They interact functionally and via shared carbon …
Nutrient-induced metabolic stress, adaptation, detoxification, and toxicity in the pancreatic β-cell
Paraphrasing the Swiss physician and father of toxicology Paracelsus (1493–1541) on
chemical agents used as therapeutics,“the dose makes the poison,” it is now realized that …
chemical agents used as therapeutics,“the dose makes the poison,” it is now realized that …
[HTML][HTML] Mitochondrial dysfunction in metabolic disorders induced by per-and polyfluoroalkyl substance mixtures in zebrafish larvae
Several per-and polyfluoroalkyl substances (PFAS) have been linked to metabolic disorders
in organisms. However, few studies have considered their combined effects, which would be …
in organisms. However, few studies have considered their combined effects, which would be …
The endocannabinoid N-arachidonoyl dopamine is critical for hyperalgesia induced by chronic sleep disruption
Chronic pain is highly prevalent and is linked to a broad range of comorbidities, including
sleep disorders. Epidemiological and clinical evidence suggests that chronic sleep …
sleep disorders. Epidemiological and clinical evidence suggests that chronic sleep …
Glycerol 3-phosphate phosphatase/PGPH-2 counters metabolic stress and promotes healthy aging via a glycogen sensing-AMPK-HLH-30-autophagy axis in C …
E Possik, LL Klein, P Sanjab, R Zhu, L Côté… - Nature …, 2023 - nature.com
Metabolic stress caused by excess nutrients accelerates aging. We recently demonstrated
that the newly discovered enzyme glycerol-3-phosphate phosphatase (G3PP; gene Pgp) …
that the newly discovered enzyme glycerol-3-phosphate phosphatase (G3PP; gene Pgp) …
Application of Caenorhabditis elegans in Lipid Metabolism Research
L An, X Fu, J Chen, J Ma - International journal of molecular sciences, 2023 - mdpi.com
Over the last decade, the development and prevalence of obesity have posed a serious
public health risk, which has prompted studies on the regulation of adiposity. With the ease …
public health risk, which has prompted studies on the regulation of adiposity. With the ease …