Background Nucleic acid aptamers, defined as small functional nucleic acids that can
selectively bind to a specific target, have become one of the main bio-recognition elements …

Biorefinery of biomass-based biofuels and biochemicals by microorganisms is a competitive
alternative of traditional petroleum refineries. Zymomonas mobilis is a natural ethanologen …

The predominant mutation causing cystic fibrosis, a deletion of phenylalanine 508 (Δ508) in
the cystic fibrosis transmembrane conductance regulator (CFTR), leads to severe defects in …

Small molecule chaperones have been exploited as therapeutics for the hundreds of
diseases caused by protein misfolding. The most successful examples are the CFTR …

Biodegradation of synthetic polymers, in particular polyethylene terephthalate (PET), is of
great importance, since environmental pollution with PET and other plastics has become a …

Abstract Vibrio cholerae biotype El Tor is perpetuating the longest cholera pandemic in
recorded history. The genomic islands VSP-1 and VSP-2 distinguish El Tor from previous …

The function of RNA is subtly modulated by post-transcriptional modifications. Here, we
report an important crosstalk in the covalent modification of two classes of RNAs. We …

Soluble angiotensin-converting enzyme 2 (ACE2) constitutes an attractive antiviral capable
of targeting a wide range of coronaviruses using ACE2 as their receptor. Using structure …

Seed germination and flowering initiation are both transitions responding to similar seasonal
cues. This study shows that ABSCISIC ACID-INSENSITIVE MUTANT 5 (ABI5), a bZIP …

The membrane receptor kinases HAESA and HSL2 recognize a family of IDA/IDL signaling
peptides to control cell separation processes in different plant organs. The homologous …