[HTML][HTML] Light pollution, circadian photoreception, and melatonin in vertebrates

M Grubisic, A Haim, P Bhusal, DM Dominoni… - Sustainability, 2019 - mdpi.com
Artificial light at night (ALAN) is increasing exponentially worldwide, accelerated by the
transition to new efficient lighting technologies. However, ALAN and resulting light pollution …

Brain washing and neural health: role of age, sleep, and the cerebrospinal fluid melatonin rhythm

RJ Reiter, R Sharma, MS Cucielo, DX Tan… - Cellular and Molecular …, 2023 - Springer
The brain lacks a classic lymphatic drainage system. How it is cleansed of damaged
proteins, cellular debris, and molecular by-products has remained a mystery for decades …

High sensitivity and interindividual variability in the response of the human circadian system to evening light

AJK Phillips, P Vidafar, AC Burns… - Proceedings of the …, 2019 - pnas.org
Before the invention of electric lighting, humans were primarily exposed to intense (> 300
lux) or dim (< 30 lux) environmental light—stimuli at extreme ends of the circadian system's …

Melatonin suppression is exquisitely sensitive to light and primarily driven by melanopsin in humans

AS Prayag, RP Najjar, C Gronfier - Journal of pineal research, 2019 - Wiley Online Library
Introduction Light elicits a range of non‐visual responses in humans. Driven predominantly
by intrinsically photosensitive retinal ganglion cells (ipRGCs), but also by rods and/or cones …

Evening home lighting adversely impacts the circadian system and sleep

SW Cain, EM McGlashan, P Vidafar, J Mustafovska… - Scientific reports, 2020 - nature.com
The regular rise and fall of the sun resulted in the development of 24-h rhythms in virtually all
organisms. In an evolutionary heartbeat, humans have taken control of their light …

The cognitive impact of light: illuminating ipRGC circuit mechanisms

HL Mahoney, TM Schmidt - Nature Reviews Neuroscience, 2024 - nature.com
Ever-present in our environments, light entrains circadian rhythms over long timescales,
influencing daily activity patterns, health and performance. Increasing evidence indicates …

[HTML][HTML] Melanopsin contributions to non-visual and visual function

M Spitschan - Current opinion in behavioral sciences, 2019 - Elsevier
Melanopsin is a short-wavelength-sensitive photopigment that was discovered only around
20 years ago. It is expressed in the cell bodies and processes of a subset of retinal ganglion …

[HTML][HTML] Blue light and temperature actigraphy measures predicting metabolic health are linked to melatonin receptor polymorphism

D Gubin, K Danilenko, O Stefani, S Kolomeichuk… - Biology, 2023 - mdpi.com
Simple Summary We examined the relationship between the circadian rhythms of activity,
wrist temperature (wT), blue light exposure (BLE) and sleep with proxies of metabolic health …

Evidence that the woman's ovarian cycle is driven by an internal circamonthly timing system

R Ecochard, JB Stanford, RJ Fehring, M Schneider… - Science …, 2024 - science.org
The ovarian cycle has a well-established circa-monthly rhythm, but the mechanisms
involved in its regularity are unknown. Is the rhythmicity driven by an endogenous clock-like …

Attenuation of short wavelengths alters sleep and the IP RGC pupil response

LA Ostrin, KS Abbott… - … and Physiological Optics, 2017 - Wiley Online Library
Purpose Exposure to increasing amounts of artificial light during the night may contribute to
the high prevalence of reported sleep dysfunction. Release of the sleep hormone melatonin …