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[HTML][HTML] Light pollution, circadian photoreception, and melatonin in vertebrates
Artificial light at night (ALAN) is increasing exponentially worldwide, accelerated by the
transition to new efficient lighting technologies. However, ALAN and resulting light pollution …
transition to new efficient lighting technologies. However, ALAN and resulting light pollution …
Brain washing and neural health: role of age, sleep, and the cerebrospinal fluid melatonin rhythm
The brain lacks a classic lymphatic drainage system. How it is cleansed of damaged
proteins, cellular debris, and molecular by-products has remained a mystery for decades …
proteins, cellular debris, and molecular by-products has remained a mystery for decades …
High sensitivity and interindividual variability in the response of the human circadian system to evening light
Before the invention of electric lighting, humans were primarily exposed to intense (> 300
lux) or dim (< 30 lux) environmental light—stimuli at extreme ends of the circadian system's …
lux) or dim (< 30 lux) environmental light—stimuli at extreme ends of the circadian system's …
Melatonin suppression is exquisitely sensitive to light and primarily driven by melanopsin in humans
Introduction Light elicits a range of non‐visual responses in humans. Driven predominantly
by intrinsically photosensitive retinal ganglion cells (ipRGCs), but also by rods and/or cones …
by intrinsically photosensitive retinal ganglion cells (ipRGCs), but also by rods and/or cones …
Evening home lighting adversely impacts the circadian system and sleep
The regular rise and fall of the sun resulted in the development of 24-h rhythms in virtually all
organisms. In an evolutionary heartbeat, humans have taken control of their light …
organisms. In an evolutionary heartbeat, humans have taken control of their light …
The cognitive impact of light: illuminating ipRGC circuit mechanisms
HL Mahoney, TM Schmidt - Nature Reviews Neuroscience, 2024 - nature.com
Ever-present in our environments, light entrains circadian rhythms over long timescales,
influencing daily activity patterns, health and performance. Increasing evidence indicates …
influencing daily activity patterns, health and performance. Increasing evidence indicates …
[HTML][HTML] Melanopsin contributions to non-visual and visual function
M Spitschan - Current opinion in behavioral sciences, 2019 - Elsevier
Melanopsin is a short-wavelength-sensitive photopigment that was discovered only around
20 years ago. It is expressed in the cell bodies and processes of a subset of retinal ganglion …
20 years ago. It is expressed in the cell bodies and processes of a subset of retinal ganglion …
[HTML][HTML] Blue light and temperature actigraphy measures predicting metabolic health are linked to melatonin receptor polymorphism
Simple Summary We examined the relationship between the circadian rhythms of activity,
wrist temperature (wT), blue light exposure (BLE) and sleep with proxies of metabolic health …
wrist temperature (wT), blue light exposure (BLE) and sleep with proxies of metabolic health …
Evidence that the woman's ovarian cycle is driven by an internal circamonthly timing system
R Ecochard, JB Stanford, RJ Fehring, M Schneider… - Science …, 2024 - science.org
The ovarian cycle has a well-established circa-monthly rhythm, but the mechanisms
involved in its regularity are unknown. Is the rhythmicity driven by an endogenous clock-like …
involved in its regularity are unknown. Is the rhythmicity driven by an endogenous clock-like …
Attenuation of short wavelengths alters sleep and the IP RGC pupil response
LA Ostrin, KS Abbott… - … and Physiological Optics, 2017 - Wiley Online Library
Purpose Exposure to increasing amounts of artificial light during the night may contribute to
the high prevalence of reported sleep dysfunction. Release of the sleep hormone melatonin …
the high prevalence of reported sleep dysfunction. Release of the sleep hormone melatonin …