Next generation probiotics: Engineering live biotherapeutics

SK Murali, TJ Mansell - Biotechnology Advances, 2024 - Elsevier
The population dynamics of the human microbiome have been associated with inflammatory
bowel disease, cancer, obesity, autoimmune diseases, and many other human disease …

Yeasts as probiotics: Mechanisms, outcomes, and future potential

S Sen, TJ Mansell - Fungal Genetics and Biology, 2020 - Elsevier
The presence of commensal fungal species in the human gut indicates that organisms from
this kingdom have the potential to benefit the host as well. Saccharomyces boulardii, a yeast …

Exploring the journey: a comprehensive review of vaccine development against Klebsiella pneumoniae

B Douradinha - Microbiological Research, 2024 - Elsevier
Klebsiella pneumoniae, a prominent nosocomial pathogen, poses a critical global health
threat due to its multidrug-resistant (MDR) and hypervirulent strains. This comprehensive …

Health-promoting properties of Saccharomyces cerevisiae var. boulardii as a probiotic; characteristics, isolation, and applications in dairy products

F Ansari, S Alian Samakkhah, A Bahadori… - Critical reviews in …, 2023 - Taylor & Francis
Saccharomyces cerevisiae var. boulardii (S. boulardii) has been isolated from lychee (Litchi
chinensis), mangosteen fruit, kombucha, and dairy products like kefir. Dairy products …

A probiotic yeast-based immunotherapy against Clostridioides difficile infection

K Chen, Y Zhu, Y Zhang, T Hamza, H Yu… - Science translational …, 2020 - science.org
Antibiotic-resistant Clostridioides difficile is an anaerobic Gram-positive bacterium that
colonizes the colon and is responsible for more than 29,000 deaths in the United States …

Probiotic Saccharomyces cerevisiae strains as biotherapeutic tools: is there room for improvement?

ML Palma, D Zamith-Miranda, FS Martins… - Applied Microbiology …, 2015 - Springer
The probiotic yeast Saccharomyces cerevisiae var boulardii is widely used as a low cost and
efficient adjuvant against gastrointestinal tract disorders such as inflammatory bowel …

Metabolic engineering of probiotic Saccharomyces boulardii

JJ Liu, II Kong, GC Zhang, LN Jayakody… - Applied and …, 2016 - journals.asm.org
Saccharomyces boulardii is a probiotic yeast that has been used for promoting gut health as
well as preventing diarrheal diseases. This yeast not only exhibits beneficial phenotypes for …

Characterization of the Probiotic Yeast Saccharomyces boulardii in the Healthy Mucosal Immune System

LE Hudson, CD McDermott, TP Stewart, WH Hudson… - PloS one, 2016 - journals.plos.org
The probiotic yeast Saccharomyces boulardii has been shown to ameliorate disease
severity in the context of many infectious and inflammatory conditions. However, use of S …

Oral Administration of Recombinant Saccharomyces boulardii Expressing Ovalbumin-CPE Fusion Protein Induces Antibody Response in Mice

G Bagherpour, H Ghasemi, B Zand, N Zarei… - Frontiers in …, 2018 - frontiersin.org
Saccharomyces boulardii, a subspecies of Saccharomyces cerevisiae, is a well-known
eukaryotic probiotic with many benefits for human health. In the present study, a …

The monitoring, via an in vitro digestion system, of the bioactive content of vegetable juice fermented with Saccharomyces cerevisiae and Saccharomyces boulardii

N Değirmencioğlu, O Gurbuz… - Journal of Food …, 2016 - Wiley Online Library
In the present study, an in vitro model simulating gastro‐intestinal (GI) digestion, was
adapted to assess phenolic compounds from watermelon radish (R), red beet (RB) and …