RNA-binding proteins (RBPs) modulate the expression level of several target RNAs (such as
mRNAs) post-transcriptionally through interactions with unique binding sites in the 3 …

Hypoxia and elevated extracellular acidification are prevalent features of solid tumors and
they are often shown to facilitate cancer progression and drug resistance. In this review, we …

Cross-talk between the tumor microenvironment (TME) and cancer cells plays an important
role in acquired drug resistance to epidermal growth factor receptor tyrosine kinase …

Multiple myeloma (MM) is a plasma cell malignancy of the bone marrow. Despite therapeutic
advances, MM remains incurable, and better risk stratification as well as new therapies are …

Amyloids are highly ordered fibrous cross-β protein aggregates that are notorious primarily
because of association with a variety of incurable human and animal diseases (termed …

Objective ALS is a rapidly progressive, fatal disorder caused by motor neuron degeneration,
for which there is a great unmet therapeutic need. AMX0035, a combination of sodium …

Fragile X syndrome (FXS) is caused by inactivation of the FMR1 gene and loss of encoded
FMRP, an RNA binding protein that represses translation of some of its target transcripts …

Prostate stromal cells play a crucial role in the promotion of tumor growth and immune
evasion in the tumor microenvironment (TME) through intricate molecular alterations in their …

Background The growing body of evidence suggests that RNA-binding proteins (RBPs)
have an important function in cancer biology. This research characterizes the expression …

The fragile X-related (FXR) family proteins FMRP, FXR1, and FXR2 are RNA binding
proteins that play a critical role in RNA metabolism, neuronal plasticity, and muscle …