Berberine-containing plants have been traditionally used in different parts of the world for
the treatment of inflammatory disorders, skin diseases, wound healing, reducing fevers …

Besides being important occupational hazards, lead and cadmium are nowadays metals of
great environmental concern. Both metals, without any physiological functions, can induce …

Berberine, a benzylisoquinoline alkaloid, occurs as an active constituent in numerous
medicinal plants and has an array of pharmacological properties. It has been used in …

Objective Mercury is a global environmental pollutant and is responsible for several organ
pathophysiology including oxidative stress-induced liver disorders. Therefore, the present …

Diabetes mellitus is a group of metabolic disorders characterized by hyperglycemia caused
by resistance to insulin action, inadequate insulin secretion, or excessive glucagon …

Hepatotoxicity is one of the major side effects of methotrexate (MTX), which restricts the
clinical use of this drug. Berberine (BBR) is a natural compound with multiple …

Liver plays an important role in bile synthesis, metabolic function, degradation of toxins, new
substances synthesis in body. However, hepatopathy morbidity and mortality are increasing …

The present study was conducted to investigate the protective effects of hesperidin (HSP)
against sodium arsenite (SA)-induced nephrotoxicity and hepatotoxicity in rats. Thirty-five …

Phellodendri Chinese Cortex has long been used to treat hyperuricemia and gout.
Berberine (BBR), its characteristic ingredient, has also been shown to be effective in …

This study aimed to investigate the potential protective role of Physalis peruviana L.(family
Solanaceae) against cadmium-induced hepatorenal toxicity in Wistar rats. Herein, cadmium …