Skin tissue regeneration for burn injury

A Shpichka, D Butnaru, EA Bezrukov… - Stem cell research & …, 2019 - Springer
The skin is the largest organ of the body, which meets the environment most directly. Thus,
the skin is vulnerable to various damages, particularly burn injury. Skin wound healing is a …

Development and use of biomaterials as wound healing therapies

RZ Murray, ZE West, AJ Cowin, BL Farrugia - Burns & trauma, 2019 - academic.oup.com
There is a vast number of treatments on the market for the management of wounds and
burns, representing a multi-billion dollar industry worldwide. These include conventional …

Scarless wound healing: finding the right cells and signals

T Leavitt, MS Hu, CD Marshall, LA Barnes… - Cell and tissue …, 2016 - Springer
From the moment we are born, every injury to the skin has the potential to form a scar, many
of which can impair form and/or function. As such, scar management constitutes a billion …

Stem cells and engineered scaffolds for regenerative wound healing

BC Dash, Z Xu, L Lin, A Koo, S Ndon, F Berthiaume… - Bioengineering, 2018 - mdpi.com
The normal wound healing process involves a well-organized cascade of biological
pathways and any failure in this process leads to wounds becoming chronic. Non-healing …

Bio-fabricated nanocomposite hydrogel with ROS scavenging and local oxygenation accelerates diabetic wound healing

Y Pu, P Wang, R Yang, X Tan, T Shi, J Ma… - Journal of Materials …, 2022 - pubs.rsc.org
Chronic wounds, especially diabetic wounds, involve abnormally long inflammatory periods
due to their pathological microenvironment of high reactive oxygen species (ROS) levels …

Fibrin-based delivery strategies for acute and chronic wound healing

P Heher, S Mühleder, R Mittermayr, H Redl… - Advanced drug delivery …, 2018 - Elsevier
Fibrin, a natural hydrogel, is the end product of the physiological blood coagulation cascade
and naturally involved in wound healing. Beyond its role in hemostasis, it acts as a local …

Pathogenesis of wound healing disorders in the elderly

E Makrantonaki, M Wlaschek… - JDDG: Journal der …, 2017 - Wiley Online Library
The elderly constitute the age group most susceptible to wound healing disorders and
chronic wounds, the most prevalent being venous leg ulcers, pressure ulcers, and diabetic …

An overview of the therapeutic potential of regenerative medicine in cutaneous wound healing

C Pang, A Ibrahim, NW Bulstrode… - International Wound …, 2017 - Wiley Online Library
The global burden of disease associated with wounds is an increasingly significant public
health concern. Current treatments are often expensive, time‐consuming and limited in their …

Transplantation of photobiomodulation-preconditioned diabetic stem cells accelerates ischemic wound healing in diabetic rats

H Ahmadi, A Amini, F Fadaei Fathabady… - Stem cell research & …, 2020 - Springer
Background Diabetic foot ulcer is the most costly and complex challenge for patients with
diabetes. We hereby assessed the effectiveness of different preconditioned adipose-derived …

Wound healing: time to look for intelligent,'natural'immunological approaches?

O Garraud, WN Hozzein, G Badr - BMC immunology, 2017 - Springer
There is now good evidence that cytokines and growth factors are key factors in tissue repair
and often exert anti-infective activities. However, engineering such factors for global use …