Research on the use of biodegradable polymers for drug delivery has been ongoing since
they were first used as bioresorbable surgical devices in the 1980s. For tissue engineering …

Therapeutics are habitually characterized by short plasma half-lives and little affinity for
targeted cells. To overcome these challenges, nanoparticulate systems have entered into …

Abstract Epigallocatechin-3-gallate (EGCG) is a candidate for treatment of Alzheimer's
disease (AD) but its inherent instability limits bioavailability and effectiveness. We found that …

Poly (lactic-co-glycolic acid) nanoparticles (PLGA NPs) are well recognized as an ideal drug
delivery carrier for their biocompatibility and biodegradability. In order to overcome the …

Due to the dangerous side effects of chemotherapy, advanced methods for curing cancer,
such as drug delivery, have attracted much attention because of their high efficacies. Using …

Over the past two decades, multidisciplinary investigations into the development of
nanoparticles for medical applications have continually increased. However, nanoparticles …

Cancers are heterogeneous at the cell level, and the mechanisms leading to cancer
heterogeneity could be clonal evolution or cancer stem cells. Cancer stem cells are resistant …

To date, hydrogels have opened new prospects for potential applications for drug delivery.
The thermo-sensitive hydrogels have the great potential to provide more effective and …

The aim of this study was to develop and characterize 5-Fluorouracil (5FU) containing
targeted liposomes in order to enhance the efficacy and safety of the drug. Folic acid (FA) …

Breast cancer is one of the most prevalent types of cancer among female patients, which is
caused by mutations in the oestrogen/progesterone receptors. Conventional treatment …