Optimal transport for single-cell and spatial omics

C Bunne, G Schiebinger, A Krause, A Regev… - Nature Reviews …, 2024 - nature.com
High-throughput single-cell profiling provides an unprecedented ability to uncover the
molecular states of millions of cells. These technologies are, however, destructive to cells …

Recent advances in optimal transport for machine learning

EF Montesuma, FMN Mboula… - IEEE Transactions on …, 2024 - ieeexplore.ieee.org
Recently, Optimal Transport has been proposed as a probabilistic framework in Machine
Learning for comparing and manipulating probability distributions. This is rooted in its rich …

Screening cell–cell communication in spatial transcriptomics via collective optimal transport

Z Cang, Y Zhao, AA Almet, A Stabell, R Ramos… - Nature …, 2023 - nature.com
Spatial transcriptomic technologies and spatially annotated single-cell RNA sequencing
datasets provide unprecedented opportunities to dissect cell–cell communication (CCC) …

Inferring spatial and signaling relationships between cells from single cell transcriptomic data

Z Cang, Q Nie - Nature communications, 2020 - nature.com
Single-cell RNA sequencing (scRNA-seq) provides details for individual cells; however,
crucial spatial information is often lost. We present SpaOTsc, a method relying on structured …

Pot: Python optimal transport

R Flamary, N Courty, A Gramfort, MZ Alaya… - Journal of Machine …, 2021 - jmlr.org
Optimal transport has recently been reintroduced to the machine learning community thanks
in part to novel efficient optimization procedures allowing for medium to large scale …

Gene expression cartography

M Nitzan, N Karaiskos, N Friedman, N Rajewsky - Nature, 2019 - nature.com
Multiplexed RNA sequencing in individual cells is transforming basic and clinical life
sciences,,–. Often, however, tissues must first be dissociated, and crucial information about …

Map** cells through time and space with moscot

D Klein, G Palla, M Lange, M Klein, Z Piran, M Gander… - Nature, 2025 - nature.com
Single-cell genomic technologies enable the multimodal profiling of millions of cells across
temporal and spatial dimensions. However, experimental limitations hinder the …

Rates of estimation of optimal transport maps using plug-in estimators via barycentric projections

N Deb, P Ghosal, B Sen - Advances in Neural Information …, 2021 - proceedings.neurips.cc
Optimal transport maps between two probability distributions $\mu $ and $\nu $ on $\R^ d $
have found extensive applications in both machine learning and statistics. In practice, these …

Minimax estimation of discontinuous optimal transport maps: The semi-discrete case

AA Pooladian, V Divol… - … Conference on Machine …, 2023 - proceedings.mlr.press
We consider the problem of estimating the optimal transport map between two probability
distributions, $ P $ and $ Q $ in $\mathbb {R}^ d $, on the basis of iid samples. All existing …

Minimax estimation of smooth optimal transport maps

JC Hütter, P Rigollet - 2021 - projecteuclid.org
The supplementary materials contain more background on convex functions, wavelets and
empirical processes, as well as tools to prove lower bounds, alternative assumptions based …