Exosomes are small bilipid layer-enclosed extracellular vesicles that can be found in tissues
and biological fluids. As a key cell-to-cell and distant communication mediator, exosomes …

Seizures result from hypersynchronous, abnormal firing of neuronal populations and are the
primary clinical symptom of the epilepsies. Brain tissue from animal models and patients …

Neural stem cells residing in the hippocampal neurogenic niche sustain lifelong
neurogenesis in the adult brain. Adult hippocampal neurogenesis (AHN) is functionally …

Temporal lobe epilepsy is a common, chronic neurological disorder characterized by
recurrent spontaneous seizures. MicroRNAs (miRNAs) are small, noncoding RNAs that …

Background Temporal lobe epilepsy is a common and frequently intractable seizure
disorder. Its pathogenesis is thought to involve large-scale alterations to the expression of …

During the last two decades, microRNAs (miRNAs) emerged as critical regulators of gene
expression. By modulating the expression of numerous target mRNAs mainly at the post …

MicroRNAs are small noncoding RNAs that regulate gene expression at the
posttranscriptional level in a sequence-specific manner. After their discovery in 1993 …

Since aberrant miRNA expression has been implicated in numerous brain diseases, we
studied miRNA expression and miRNA regulation of important signaling pathways during …

Abstract microRNA‐132 (miR‐132) is involved in prosurvival, anti‐inflammatory and memory‐
promoting functions in the nervous system and has been found consistently downregulated …

Background The expression pattern and function of miRNAs in the rat model of temporal
lobe epilepsy have not been well defined. Profiling miRNA expression in the rat model of …