Deficient mismatch repair/microsatellite unstable colorectal cancer: Diagnosis, prognosis and treatment

J Taieb, M Svrcek, R Cohen, D Basile… - European Journal of …, 2022 - Elsevier
Microsatellite unstable (MSI) colorectal cancers (CRCs) are due to DNA mismatch repair
(MMR) deficiency and occurs in15% of non-metastatic diseases and 5% in the metastatic …

[HTML][HTML] The risk of sexual transmission of HIV in individuals with low-level HIV viraemia: a systematic review

LN Broyles, R Luo, D Boeras, L Vojnov - The Lancet, 2023 - thelancet.com
Background The risk of sexual transmission of HIV from individuals with low-level HIV
viraemia receiving antiretroviral therapy (ART) has important public health implications …

[HTML][HTML] Sample size, power and effect size revisited: simplified and practical approaches in pre-clinical, clinical and laboratory studies

CC Serdar, M Cihan, D Yücel, MA Serdar - Biochemia medica, 2021 - hrcak.srce.hr
Sažetak Calculating the sample size in scientific studies is one of the critical issues as
regards the scientific contribution of the study. The sample size critically affects the …

Deep learning-aided decision support for diagnosis of skin disease across skin tones

M Groh, O Badri, R Daneshjou, A Koochek, C Harris… - Nature Medicine, 2024 - nature.com
Although advances in deep learning systems for image-based medical diagnosis
demonstrate their potential to augment clinical decision-making, the effectiveness of …

[HTML][HTML] Meta-analysis of tumor-and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition

K Litchfield, JL Reading, C Puttick, K Thakkar… - Cell, 2021 - cell.com
Checkpoint inhibitors (CPIs) augment adaptive immunity. Systematic pan-tumor analyses
may reveal the relative importance of tumor-cell-intrinsic and microenvironmental features …

Development and validation of a risk-of-bias tool for assessing in vitro studies conducted in dentistry: The QUIN

VH Sheth, NP Shah, R Jain, N Bhanushali… - The Journal of Prosthetic …, 2024 - Elsevier
Statement of problem Systematic reviews and meta-analyses have emerged as forerunners
of evidence-based dentistry, but assessing the quality of the available research is essential …

The biological meaning of radiomic features

MR Tomaszewski, RJ Gillies - Radiology, 2021 - pubs.rsna.org
Radiomic analysis offers a powerful tool for the extraction of clinically relevant information
from radiologic imaging. Radiomics can be used to predict patient outcome through …

Prostate-specific membrane antigen PET-CT in patients with high-risk prostate cancer before curative-intent surgery or radiotherapy (proPSMA): a prospective …

MS Hofman, N Lawrentschuk, RJ Francis, C Tang… - The Lancet, 2020 - thelancet.com
Background Conventional imaging using CT and bone scan has insufficient sensitivity when
staging men with high-risk localised prostate cancer. We aimed to investigate whether novel …

Checklist for artificial intelligence in medical imaging (CLAIM): a guide for authors and reviewers

J Mongan, L Moy, CE Kahn Jr - Radiology: Artificial Intelligence, 2020 - pubs.rsna.org
Study Design Item 5. Indicate if the study is retrospective or prospective. Evaluate predictive
models in a prospective setting, if possible. Item 6. Define the study's goal, such as model …

Artificial intelligence and the future of global health

N Schwalbe, B Wahl - The Lancet, 2020 - thelancet.com
Concurrent advances in information technology infrastructure and mobile computing power
in many low and middle-income countries (LMICs) have raised hopes that artificial …