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Deuterium‐and tritium‐labelled compounds: applications in the life sciences
J Atzrodt, V Derdau, WJ Kerr… - Angewandte chemie …, 2018 - Wiley Online Library
Hydrogen isotopes are unique tools for identifying and understanding biological and
chemical processes. Hydrogen isotope labelling allows for the traceless and direct …
chemical processes. Hydrogen isotope labelling allows for the traceless and direct …
LC-MS-based metabolomics
Metabolomics aims at identification and quantitation of small molecules involved in
metabolic reactions. LC-MS has enjoyed a growing popularity as the platform for …
metabolic reactions. LC-MS has enjoyed a growing popularity as the platform for …
Toxicity mechanisms of polystyrene microplastics in marine mussels revealed by high-coverage quantitative metabolomics using chemical isotope labeling liquid …
Marine microplastic has become an important environmental issue of global concern due to
its wide distribution and harmful impacts. However, there is still insufficient information on …
its wide distribution and harmful impacts. However, there is still insufficient information on …
An isotope-labeled chemical derivatization method for the quantitation of short-chain fatty acids in human feces by liquid chromatography–tandem mass spectrometry
Short-chain fatty acids (SCFAs) are produced by anaerobic gut microbiota in the large
bowel. Qualitative and quantitative measurements of SCFAs in the intestinal tract and the …
bowel. Qualitative and quantitative measurements of SCFAs in the intestinal tract and the …
Mass spectrometric based approaches in urine metabolomics and biomarker discovery
Urine metabolomics has recently emerged as a prominent field for the discovery of non‐
invasive biomarkers that can detect subtle metabolic discrepancies in response to a specific …
invasive biomarkers that can detect subtle metabolic discrepancies in response to a specific …
Metabolomic coverage of chemical-group-submetabolome analysis: group classification and four-channel chemical isotope labeling LC-MS
Chemical isotope labeling (CIL) liquid chromatography mass spectrometry (LC-MS) is a
powerful technique for in-depth metabolome analysis with high quantification accuracy …
powerful technique for in-depth metabolome analysis with high quantification accuracy …
Stable isotope-labeling studies in metabolomics: new insights into structure and dynamics of metabolic networks
The rapid emergence of metabolomics has enabled system-wide measurements of
metabolites in various organisms. However, advances in the mechanistic understanding of …
metabolites in various organisms. However, advances in the mechanistic understanding of …
Advances and perspectives in chemical isotope labeling-based mass spectrometry methods for metabolome and exposome analysis
S Gao, X Zhou, M Yue, S Zhu, Q Liu, XE Zhao - TrAC Trends in Analytical …, 2023 - Elsevier
Metabolomics and exposomics are important in the studies of human health and diseases.
Chemical isotope labeling (CIL) combined with mass spectrometry (MS) can not only …
Chemical isotope labeling (CIL) combined with mass spectrometry (MS) can not only …
MyCompoundID: using an evidence-based metabolome library for metabolite identification
Identification of unknown metabolites is a major challenge in metabolomics. Without the
identities of the metabolites, the metabolome data generated from a biological sample …
identities of the metabolites, the metabolome data generated from a biological sample …
Fast quantification of short chain fatty acids and ketone bodies by liquid chromatography-tandem mass spectrometry after facile derivatization coupled with liquid …
M Zeng, H Cao - Journal of Chromatography B, 2018 - Elsevier
Short chain fatty acids (SCFA) and ketone bodies recently emerged as important
physiological relevant metabolites because of their association with microbiota …
physiological relevant metabolites because of their association with microbiota …