Radiation-induced lung injury: assessment and management

AN Hanania, W Mainwaring, YT Ghebre, NA Hanania… - Chest, 2019 - Elsevier
Radiation-induced lung injury (RILI) encompasses any lung toxicity induced by radiation
therapy (RT) and manifests acutely as radiation pneumonitis and chronically as radiation …

Combining radiation and immunotherapy: a new systemic therapy for solid tumors?

C Tang, X Wang, H Soh, S Seyedin, MA Cortez… - Cancer immunology …, 2014 - AACR
With the recent success of checkpoint inhibitors and other immunomodulating agents, there
has been renewed interest in the combination of such agents with radiation. The biologic …

Organising pneumonia

JF Cordier - Thorax, 2000 - thorax.bmj.com
Organising pneumonia is defined pathologically by the presence in the distal air spaces of
buds of granulation tissue progressing from fibrin exudates to loose collagen containing …

Factors predicting severe radiation pneumonitis in patients receiving definitive chemoradiation for lung cancer

TJ Robnett, M Machtay, EF Vines, MG McKenna… - International Journal of …, 2000 - Elsevier
Purpose: To identify factors that may predict for severe radiation pneumonitis or
pneumonopathy (RP), we reviewed a set of simple, commonly available characteristics …

Pulmonary radiation injury

B Movsas, TA Raffin, AH Epstein, CJ Link - Chest, 1997 - journal.chestnet.org
T he fundamental ability to successfully treat any neoplasm ultimately depends on the
therapeutic ratio, ie, the ability to sterilize the tumor while sparing normal tissues. There are …

Radiation and the lung: a reevaluation of the mechanisms mediating pulmonary injury

GW Morgan, B Pharm, SN Breit - International Journal of Radiation …, 1995 - Elsevier
Recent data from several investigators, including our unit, have provided additional
information on the etiology of radiation-induced lung damage. These data suggest that there …

Radiation pneumonitis and early circulatory cytokine markers

Y Chen, J Williams, I Ding, E Hernady, W Liu… - Seminars in radiation …, 2002 - Elsevier
Radiation pneumonitis is a distinct clinical entity that differs from other pulmonary symptoms
such as allergic pneumonitis, chemical pneumonitis, or pneumonia by various infectious …

The epidemiology of interstitial lung disease and its association with lung cancer

G Raghu, F Nyberg, G Morgan - British Journal of Cancer, 2004 - nature.com
The criteria and terminology for diagnosing interstitial lung disease (ILD), a diverse range of
pulmonary fibrotic disorders that affect the alveoli of the lungs, have been variable and …

Clinical radiation pneumonitis and radiographic changes after thoracic radiation therapy for lung carcinoma

JM Monson, P Stark, JJ Reilly… - … Journal of The …, 1998 - Wiley Online Library
BACKGROUND The authors attempted to determine the incidence of and risk factors for
clinical radiation pneumonitis in patients treated for lung carcinoma. They also sought to …

The role of lymphocytes in radiotherapy-induced adverse late effects in the lung

F Wirsdörfer, V Jendrossek - Frontiers in immunology, 2016 - frontiersin.org
Radiation-induced pneumonitis and fibrosis are dose-limiting side effects of thoracic
irradiation. Thoracic irradiation triggers acute and chronic environmental lung changes that …