Laser ablation–inductively coupled plasma–mass spectrometry imaging in biology

PA Doble, RG de Vega, DP Bishop, DJ Hare… - Chemical …, 2021 - ACS Publications
Elemental imaging gives insight into the fundamental chemical makeup of living organisms.
Every cell on Earth is comprised of a complex and dynamic mixture of the chemical elements …

Recent advances in quantitative LA-ICP-MS analysis: challenges and solutions in the life sciences and environmental chemistry

A Limbeck, P Galler, M Bonta, G Bauer… - Analytical and …, 2015 - Springer
Laser ablation–inductively coupled plasma–mass spectrometry (LA-ICP-MS) is a widely
accepted method for direct sampling of solid materials for trace elemental analysis. The …

Bioimaging mass spectrometry of trace elements–recent advance and applications of LA-ICP-MS: a review

JS Becker, A Matusch, B Wu - Analytica chimica acta, 2014 - Elsevier
Bioimaging using laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS)
offers the capability to quantify trace elements and isotopes within tissue sections with a …

Analytical methods for imaging metals in biology: from transition metal metabolism to transition metal signaling

CM Ackerman, S Lee, CJ Chang - Analytical chemistry, 2017 - ACS Publications
Metal elements represent some of the most fundamental chemical building blocks of life and
are required to sustain the growth, development, and sustenance of all living organisms and …

Facets of ICP-MS and their potential in the medical sciences—Part 1: fundamentals, stand-alone and hyphenated techniques

D Clases, R Gonzalez de Vega - Analytical and Bioanalytical Chemistry, 2022 - Springer
Since its inception in the early 80s, inductively coupled plasma–mass spectrometry has
developed to the method of choice for the analysis of elements in complex biological …

Review of the applications of laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) to the analysis of biological samples

D Pozebon, GL Scheffler, VL Dressler… - Journal of Analytical …, 2014 - pubs.rsc.org
Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) has received
significant attention over the last 10 years and has been widely used for the analysis of …

Current approaches to calibration of LA-ICP-MS analysis

N Miliszkiewicz, S Walas, A Tobiasz - Journal of Analytical Atomic …, 2015 - pubs.rsc.org
For solid sample quantitative analyses by laser ablation inductively coupled plasma mass
spectrometry (LA-ICP-MS), the main analytical problem is the calibration step: evaluation of …

Quantification of low molecular weight compounds by MALDI imaging mass spectrometry–A tutorial review

I Rzagalinski, DA Volmer - Biochimica et Biophysica Acta (BBA)-Proteins …, 2017 - Elsevier
Matrix-assisted laser desorption/ionization (MALDI)-mass spectrometry imaging (MSI)
permits label-free in situ analysis of chemical compounds directly from the surface of two …

Calibration strategies for laser ablation ICP-MS in biological studies: A review

H Pan, L Feng, Y Lu, Y Han, J **ong, H Li - TrAC Trends in Analytical …, 2022 - Elsevier
Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) has attracted
attentions for its high sensitivity and sufficient spatial resolution in the in-situ analysis and …

Single-cell analysis by use of ICP-MS

S Theiner, K Loehr, G Koellensperger… - Journal of Analytical …, 2020 - pubs.rsc.org
This tutorial review article is highlighting the fundamentals, instrumentation, and most recent
trends of single-cell analysis by use of inductively coupled plasma-mass spectrometry (ICP …