[HTML][HTML] Functionalized liposomes for targeted breast cancer drug delivery
Despite the exceptional progress in breast cancer pathogenesis, prognosis, diagnosis, and
treatment strategies, it remains a prominent cause of female mortality worldwide …
treatment strategies, it remains a prominent cause of female mortality worldwide …
[HTML][HTML] The past, present, and future of breast cancer models for nanomedicine development
P Boix-Montesinos, PM Soriano-Teruel… - Advanced drug delivery …, 2021 - Elsevier
Even given recent advances in nanomedicine development of breast cancer treatment in
recent years and promising results in pre-clinical models, cancer nanomedicines often fail at …
recent years and promising results in pre-clinical models, cancer nanomedicines often fail at …
[HTML][HTML] A review of biological targets and therapeutic approaches in the management of triple-negative breast cancer
Background Triple-negative breast cancer (TNBC) is a heterogeneous, aggressive
phenotype of breast cancer with associated chemoresistance. The development of chemo-or …
phenotype of breast cancer with associated chemoresistance. The development of chemo-or …
Lipid-based nanoparticles as a pivotal delivery approach in triple negative breast cancer (TNBC) therapy
Triple-negative breast cancer is considered the most aggressive type of breast cancer
among women and the lack of expressed receptors has made treatment options …
among women and the lack of expressed receptors has made treatment options …
Erythrocyte leveraged chemotherapy (ELeCt): Nanoparticle assembly on erythrocyte surface to combat lung metastasis
Despite being the mainstay of cancer treatment, chemotherapy has shown limited efficacy
for the treatment of lung metastasis due to ineffective targeting and poor tumor accumulation …
for the treatment of lung metastasis due to ineffective targeting and poor tumor accumulation …
Systemic tumour suppression via the preferential accumulation of erythrocyte-anchored chemokine-encapsulating nanoparticles in lung metastases
Eliciting immune responses against primary tumours is hampered by their
immunosuppressive microenvironment and by the greater inaccessibility of deeper …
immunosuppressive microenvironment and by the greater inaccessibility of deeper …
Synthetic cells in biomedical applications
Synthetic cells are engineered vesicles that can mimic one or more salient features of life.
These features include directed localization, sense‐and‐respond behavior, gene …
These features include directed localization, sense‐and‐respond behavior, gene …
Dual affinity to RBCs and target cells (DART) enhances both organ-and cell type-targeting of intravascular nanocarriers
LT Ferguson, ED Hood, T Shuvaeva, VV Shuvaev… - ACS …, 2022 - ACS Publications
A long-standing goal of nanomedicine is to improve a drug's benefit by loading it into a
nanocarrier that homes solely to a specific target cell and organ. Unfortunately, nanocarriers …
nanocarrier that homes solely to a specific target cell and organ. Unfortunately, nanocarriers …
Current understandings and clinical translation of nanomedicines for breast cancer therapy
Y Jiang, Z Jiang, M Wang, L Ma - Advanced drug delivery reviews, 2022 - Elsevier
Breast cancer is one of the most frequently diagnosed cancers that is threatening women's
life. Current clinical treatment regimens for breast cancer often involve neoadjuvant and …
life. Current clinical treatment regimens for breast cancer often involve neoadjuvant and …
A rationally designed ICAM1 antibody drug conjugate eradicates late-stage and refractory triple-negative breast tumors in vivo
P Guo, J Huang, B Zhu, AC Huang, L Jiang, J Fang… - Science …, 2023 - science.org
Triple-negative breast cancer (TNBC) remains the most lethal form of breast cancer, and
effective targeted therapeutics are in urgent need to improve the poor prognosis of TNBC …
effective targeted therapeutics are in urgent need to improve the poor prognosis of TNBC …