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Identification of TBX15 as an adipose master trans regulator of abdominal obesity genes
Background Obesity predisposes individuals to multiple cardiometabolic disorders,
including type 2 diabetes (T2D). As body mass index (BMI) cannot reliably differentiate fat …
including type 2 diabetes (T2D). As body mass index (BMI) cannot reliably differentiate fat …
Chromatin accessibility and gene expression during adipocyte differentiation identify context-dependent effects at cardiometabolic GWAS loci
Chromatin accessibility and gene expression in relevant cell contexts can guide
identification of regulatory elements and mechanisms at genome-wide association study …
identification of regulatory elements and mechanisms at genome-wide association study …
GOPHER: Generator of probes for capture Hi-C experiments at high resolution
Background Target enrichment combined with chromosome conformation capturing
methodologies such as capture Hi-C (CHC) can be used to investigate spatial layouts of …
methodologies such as capture Hi-C (CHC) can be used to investigate spatial layouts of …