FOXO transcription factor family in cancer and metastasis
Y Jiramongkol, EWF Lam - Cancer and Metastasis Reviews, 2020 - Springer
Forkhead box O (FOXO) transcription factors regulate diverse biological processes, affecting
development, metabolism, stem cell maintenance and longevity. They have also been …
development, metabolism, stem cell maintenance and longevity. They have also been …
Forkhead box proteins: tuning forks for transcriptional harmony
Forkhead box (FOX) proteins are multifaceted transcription factors that are responsible for
fine-tuning the spatial and temporal expression of a broad range of genes both during …
fine-tuning the spatial and temporal expression of a broad range of genes both during …
TRRUST v2: an expanded reference database of human and mouse transcriptional regulatory interactions
H Han, JW Cho, S Lee, A Yun, H Kim… - Nucleic acids …, 2018 - academic.oup.com
Transcription factors (TFs) are major trans-acting factors in transcriptional regulation.
Therefore, elucidating TF–target interactions is a key step toward understanding the …
Therefore, elucidating TF–target interactions is a key step toward understanding the …
Benchmark and integration of resources for the estimation of human transcription factor activities
The prediction of transcription factor (TF) activities from the gene expression of their targets
(ie, TF regulon) is becoming a widely used approach to characterize the functional status of …
(ie, TF regulon) is becoming a widely used approach to characterize the functional status of …
HOCOMOCO: towards a complete collection of transcription factor binding models for human and mouse via large-scale ChIP-Seq analysis
We present a major update of the HOCOMOCO collection that consists of patterns
describing DNA binding specificities for human and mouse transcription factors. In this …
describing DNA binding specificities for human and mouse transcription factors. In this …
JASPAR 2014: an extensively expanded and updated open-access database of transcription factor binding profiles
Abstract JASPAR (http://jaspar. genereg. net) is the largest open-access database of matrix-
based nucleotide profiles describing the binding preference of transcription factors from …
based nucleotide profiles describing the binding preference of transcription factors from …
[HTML][HTML] The FOXO3-FOXM1 axis: A key cancer drug target and a modulator of cancer drug resistance
S Yao, LYN Fan, EWF Lam - Seminars in cancer biology, 2018 - Elsevier
The FOXO3 and FOXM1 forkhead box transcription factors, functioning downstream of the
essential PI3K-Akt, Ras-ERK and JNK/p38MAPK signalling cascades, are crucial for cell …
essential PI3K-Akt, Ras-ERK and JNK/p38MAPK signalling cascades, are crucial for cell …
RNA cytosine methylation and methyltransferases mediate chromatin organization and 5-azacytidine response and resistance in leukaemia
JX Cheng, L Chen, Y Li, A Cloe, M Yue, J Wei… - Nature …, 2018 - nature.com
The roles of RNA 5-methylcytosine (RNA: m5C) and RNA: m5C methyltransferases (RCMTs)
in lineage-associated chromatin organization and drug response/resistance are unclear …
in lineage-associated chromatin organization and drug response/resistance are unclear …
The forkhead-box family of transcription factors: key molecular players in colorectal cancer pathogenesis
P Laissue - Molecular cancer, 2019 - Springer
Colorectal cancer (CRC) is the third most commonly occurring cancer worldwide and the
fourth most frequent cause of death having an oncological origin. It has been found that …
fourth most frequent cause of death having an oncological origin. It has been found that …
GATA3-dependent cellular reprogramming requires activation-domain dependent recruitment of a chromatin remodeler
Background Transcription factor-dependent cellular reprogramming is integral to normal
development and is central to production of induced pluripotent stem cells. This process …
development and is central to production of induced pluripotent stem cells. This process …