Adverse effects of topical photodynamic therapy: a consensus review and approach to management

SH Ibbotson, TH Wong, CA Morton… - British Journal of …, 2019 - academic.oup.com
Background Topical photodynamic therapy (PDT) is widely used to treat superficial
nonmelanoma skin cancer and dysplasia, and is generally well tolerated. However, as with …

On the possibility of using 5-aminolevulinic acid in the light-induced destruction of microorganisms

A Zdubek, I Maliszewska - International Journal of Molecular Sciences, 2024 - mdpi.com
Antimicrobial photodynamic inactivation (aPDI) is a method that specifically kills target cells
by combining a photosensitizer and irradiation with light at the appropriate wavelength. The …

Nanoparticle-mediated combination chemotherapy and photodynamic therapy overcomes tumor drug resistance

A Khdair, D Chen, Y Patil, L Ma, QP Dou… - Journal of Controlled …, 2010 - Elsevier
Tumor drug resistance significantly limits the success of chemotherapy in the clinic. Tumor
cells utilize multiple mechanisms to prevent the accumulation of anticancer drugs at their …

Tumor-homing photosensitizer-conjugated glycol chitosan nanoparticles for synchronous photodynamic imaging and therapy based on cellular on/off system

SJ Lee, H Koo, DE Lee, S Min, S Lee, X Chen, Y Choi… - Biomaterials, 2011 - Elsevier
Herein, we developed the photosensitizer, protoporphyrin IX (PpIX), conjugated glycol
chitosan (GC) nanoparticles (PpIX–GC–NPs) as tumor-homing drug carriers with cellular …

Adverse effects of topical photodynamic therapy

SH Ibbotson - Photodermatology, photoimmunology & …, 2011 - Wiley Online Library
Background/purpose: Topical photodynamic therapy (PDT) is increasingly used in
dermatology, particularly for the treatment of superficial non‐melanoma skin cancer and …

Photodynamic therapeutic activity of indocyanine green entrapped in polymeric nanoparticles

SM El-Daly, AM Gamal-Eldeen, MAM Abo-Zeid… - Photodiagnosis and …, 2013 - Elsevier
BACKGROUND: Photodynamic therapy (PDT) is a therapeutic modality involving the use of
a photosensitizer agent activated by light of appropriate wavelength to selectively destroy …

The p53-mediated cytotoxicity of photodynamic therapy of cancer: recent advances

J Zawacka-Pankau, J Krachulec, I Grulkowski… - Toxicology and Applied …, 2008 - Elsevier
Photodynamic therapy (PDT) is a promising modality for the treatment of both pre-malignant
and malignant lesions. The mechanism of action converges mainly on the generation of …

Mechanism of cell death by 5‐aminolevulinic acid‐based photodynamic action and its enhancement by ferrochelatase inhibitors in human histiocytic lymphoma cell …

T Amo, N Kawanishi, M Uchida, H Fujita… - … biochemistry and its …, 2009 - Wiley Online Library
Photodynamic therapy (PDT) for tumors is based on the tumor‐selective accumulation of a
photosensitizer, protoporphyrin IX (PpIX), followed by irradiation with visible light. However …

Development of a prodrug of camptothecin for enhanced treatment of glioblastoma multiforme

E Checa-Chavarria, E Rivero-Buceta… - Molecular …, 2021 - ACS Publications
A novel therapeutic approach for glioblastoma multiforme (GBM) therapy has been carried
out through in vitro and in vivo testing by using the prodrug camptothecin-20-O-(5 …

Photodynamic therapy using 5-aminolevulinic acid triggered DNA damage of adenocarcinoma breast cancer and hepatocellular carcinoma cell lines

MAM Abo-Zeid, MT Abo-Elfadl, SM Mostafa - … and Photodynamic Therapy, 2018 - Elsevier
Targeting cancer cells with photosensitizer (PS) excited by appropriate laser irradiation to
release singlet oxygen as a photodynamic therapy (PDT) remains a challenge. This …