Endocytosed HSP60s use toll-like receptor 2 (TLR2) and TLR4 to activate the toll/interleukin-1 receptor signaling pathway in innate immune cells

RM Vabulas, P Ahmad-Nejad, C da Costa… - Journal of Biological …, 2001 - ASBMB
Heat shock proteins (HSPs) require no adjuvant to confer immunogenicity to bound
peptides, as if they possessed an intrinsic" danger" signature. To understand the …

Bacterial CpG‐DNA and lipopolysaccharides activate Toll‐like receptors at distinct cellular compartments

P Ahmad‐Nejad, H Häcker, M Rutz… - European journal of …, 2002 - Wiley Online Library
Recognition by innate immune cells of the pathogen associated molecular patterns (PAMP)
lipopolysaccharide (LPS) from Gram‐negative bacteria and bacterial CpG‐DNA depends on …

Transglutaminases

L Lorand, SM Conrad - Molecular and cellular biochemistry, 1984 - Springer
This paper is intended as a background to the topic of transglutaminases, while focusing on
current ideas regarding the biological roles of these enzymes. Specifically, the following …

Secretory IgA mediates retrotranscytosis of intact gliadin peptides via the transferrin receptor in celiac disease

T Matysiak-Budnik, IC Moura… - The Journal of …, 2008 - rupress.org
Celiac disease (CD) is an enteropathy resulting from an abnormal immune response to
gluten-derived peptides in genetically susceptible individuals. This immune response is …

The endoplasmic reticulum-resident heat shock protein Gp96 activates dendritic cells via the Toll-like receptor 2/4 pathway

RM Vabulas, S Braedel, N Hilf, H Singh-Jasuja… - Journal of Biological …, 2002 - ASBMB
The heat shock protein Gp96 has been shown to induce specific immune responses. On one
hand, this phenomenon is based on the specific interaction with CD91 that mediates …