Cytokines produced by immune cells contribute to the development and perpetuation of
inflammatory bowel disease (IBD), namely Crohn's disease and ulcerative colitis, by …

Inflammatory bowel disease and allergic asthma, as typical immune-mediated inflammatory
diseases (IMIDs), are associated with immune imbalance caused by complex interactions …

Microalgae are considered as attractive expression systems for the production of biologics.
As photosynthetic unicellular organisms, they do not require costly and complex media for …

Long-lived parasites evade host immunity through highly evolved molecular strategies. The
murine intestinal helminth, Heligmosomoides polygyrus, down-modulates the host immune …

The immunoregulatory cytokine TGF-β is pleiotropic due to the near-ubiquitous expression
of the TGF-β receptors TβRI and TβRII on diverse cell types. The helminth parasite …

Rheumatoid arthritis (RA) is an invalidating chronic autoimmune disorder characterized by
joint inflammation and progressive bone damage. Dietary intervention is an important …

Skin wound healing due to full thickness wounds typically results in fibrosis and scarring,
where parenchyma tissue is replaced with connective tissue. A major advance in wound …

In animal models of inflammatory colitis, pathology can be ameliorated by several intestinal
helminth parasites, including the mouse nematode Heligmosomoides polygyrus. To identify …

Successful and timely coronary reperfusion following acute ST-elevation myocardial
infarction (STEMI) is standard therapy to salvage ischaemic heart muscle. However …

Abstract The Transforming Growth Factor-β mimic (TGM) multigene family was recently
discovered in the murine intestinal parasite Heligmosomoides polygyrus. This family was …