Breast cancer is one of the most common types of cancer among women globally. It is
caused by mutations in the estrogen/progesterone receptors and conventional treatment …

Breast cancer remains a major global health issue, particularly affecting women and
contributing significantly to mortality rates. Current treatments for estrogen receptor‐positive …

Aromatase inhibitors are the most used anticancer drug group in breast cancer cases. The
development of resistance in cancer patients over time and the side effects of existing drugs …

Aromatase inhibitors used against hormone-dependent breast cancer, especially in post-
menopausal women, are very susceptible to the development of resistance due to their …

The murine tumor cell line LA-4 (also known as LA4 or LA 4) has been extensively used in~
70 studies from 1975 to present. However, the genetic characteristics have not been …

The development of embryonic cell lineages is tightly controlled by transcription factors that
regulate gene expression and chromatin organisation. To investigate the specialisation of …

The murine cutaneous sarcoma cell line TSC2ang1 has been established in 1999 and
recently been suggested to be a model for tuberous sclerosis-associated skin …

Background Malignant mesothelioma (MM) is a rare aggressive cancer primary located in
pleura and lung. MMs can be divided into biphasic, epithelioid and sarcomatoid subtypes. In …

Background Breast cancer (BC), one of the most frequent human tumors, is genetically and
histologically heterogeneous. Treatment options can be adapted according to BC subtype …

Aim: Murine tumour cell lines have been used in thousands of studies. Strikingly, it is rather
the rule than exception for most of them that not much is known about their genetic …